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featured publications

  • Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Jonathan Vogelgsang, Niels Hansen, Melina Stark, Michael Wagner, Hans Klafki, Barbara Marcos Morgado, Anke Jahn-Brodmann, Björn Schott, Hermann Esselmann, Chris Bauer, Johannes Schuchhardt, Luca Kleineidam, Steffen Wolfsgruber, Oliver Peters, Luisa-Sophie Schneider, Xiao Wang, Felix Menne, Josef Priller, Eike Spruth, Slawek Altenstein, Andrea Lohse, Anja Schneider, Klaus Fliessbach, Ina Vogt, Claudia Bartels, Frank Jessen, Ayda Rostamzadeh, Emrah Duezel, Wenzel Glanz, Enise Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris Rauchmann, Selim Guersel, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias Munk, Carolin Sanzenbacher, Annika Spottke, Nina Roy-Kluth, Michael Heneka, Frederic Brosseron, Alfredo Ramierez, Matthias Schmid, Jens Wiltfang

  • Efficient parameter estimation for ODE models of cellular processes using semi-quantitative data.

    Bioinformatics (Oxford, England)

    Authors: Domagoj Dorešić, Stephan Grein, Jan Hasenauer

  • Approximating facial expression effects on diagnostic accuracy via generative AI in medical genetics.

    Bioinformatics (Oxford, England)

    Authors: Tanviben Patel, Amna A Othman, Ömer Sümer, Fabio Hellman, Peter Krawitz, Elisabeth André, Molly E Ripper, Chris Fortney, Susan Persky, Ping Hu, Cedrik Tekendo-Ngongang, Suzanna Ledgister Hanchard, Kendall A Flaharty, Rebekah L Waikel, Dat Duong, Benjamin D Solomon

  • Stratified analyses refine association between TLR7 rare variants and severe COVID-19.

    HGG advances

    Authors: Jannik Boos, Caspar I van der Made, Gayatri Ramakrishnan, Eamon Coughlan, Rosanna Asselta, Britt-Sabina Löscher, Luca V C Valenti, Rafael de Cid, Luis Bujanda, Antonio Julià, Erola Pairo-Castineira, J Kenneth Baillie, Sandra May, Berina Zametica, Julia Heggemann, Agustín Albillos, Jesus M Banales, Jordi Barretina, Natalia Blay, Paolo Bonfanti, Maria Buti, Javier Fernandez, Sara Marsal, Daniele Prati, Luisa Ronzoni, Nicoletta Sacchi, Joachim L Schultze, Olaf Riess, Andre Franke, Konrad Rawlik, David Ellinghaus, Alexander Hoischen, Axel Schmidt, Kerstin U Ludwig

  • T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis.

    Nature neuroscience

    Authors: Shreeya Kedia, Hao Ji, Ruoqing Feng, Peter Androvic, Lena Spieth, Lu Liu, Jonas Franz, Hanna Zdiarstek, Katrin Perez Anderson, Cem Kaboglu, Qian Liu, Nicola Mattugini, Fatma Cherif, Danilo Prtvar, Ludovico Cantuti-Castelvetri, Arthur Liesz, Martina Schifferer, Christine Stadelmann, Sabina Tahirovic, Ozgun Gokce, Mikael Simons

  • High Prevalence of F2 20210G > A in Splanchnic Vein Thrombosis and Cerebral Venous Sinus Thrombosis: A Retrospective Cohort Study of Patients with Thrombosis in Atypical Sites.

    Hamostaseologie

    Authors: Dalia Khaddam, Hannah L McRae, Nadine Schwarz, Johannes Oldenburg, Bernd Pötzsch, Heiko Rühl, Sara Reda

  • Study Protocol of a Randomized, Two-Arm, Phase I/II Trial Investigating the Feasibility, Safety, and Efficacy of Local Treatment with US-Guided High-Intensity Focused Ultrasound in Combination with Palliative Chemotherapy in Inoperable Pancreatic Cancer.

    Journal of clinical medicine

    Authors: Milka Marinova, David-Alexis Khouri, Jim Küppers, Olga Ramig, Holger M Strunk, Johannes Breuers, Julia Fazaal, Christine Fuhrmann, Martin Coenen, Christian Möhring, Taotao Zhou, Xin Zhou, Thomas Anhalt, Farsaneh Sadeghlar, Marcus Thudium, Rupert Conrad, Georg Feldmann, Peter Brossart, Tim R Glowka, Jörg C Kalff, Markus Essler, Christian P Strassburg, Yon-Dschun Ko, Ingo G H Schmidt-Wolf, Maria Gonzalez-Carmona

  • Microglia contribute to neuronal synchrony despite endogenous ATP-related phenotypic transformation in acute mouse brain slices.

    Nature communications

    Authors: Péter Berki, Csaba Cserép, Zsuzsanna Környei, Balázs Pósfai, Eszter Szabadits, Andor Domonkos, Anna Kellermayer, Miklós Nyerges, Xiaofei Wei, Istvan Mody, Araki Kunihiko, Heinz Beck, He Kaikai, Wang Ya, Nikolett Lénárt, Zhaofa Wu, Miao Jing, Yulong Li, Attila I Gulyás, Ádám Dénes

  • Forward programming of hiPSCs via the transcription factor ETV2: rapid, reproducible, and cost-effective generation of highly enriched, functional endothelial cells.

    Cardiovascular research

    Authors: Sarah Rieck, Kritika Sharma, Carlotta Altringer, Michael Hesse, Christos Triantafyllou, Yanhui Zhang, Volker Busskamp, Bernd K Fleischmann

  • Emicizumab versus immunosuppressive therapy for the management of acquired hemophilia A.

    Journal of thrombosis and haemostasis : JTH

    Authors: Christina Hart, Robert Klamroth, Ulrich J Sachs, Richard Greil, Paul Knoebl, Johannes Oldenburg, Wolfgang Miesbach, Christian Pfrepper, Karolin Trautmann-Grill, Isabell Pekrul, Katharina Holstein, Hermann Eichler, Carmen Weigt, Dorothea Schipp, Sonja Werwitzke, Andreas Tiede