Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.
medRxiv : the preprint server for health sciences
Authors:
Nora I Strom, Brad Verhulst, Silviu-Alin Bacanu, Rosa Cheesman, Kirstin L Purves, Hüseyin Gedik, Brittany L Mitchell, Alex S Kwong, Annika B Faucon, Kritika Singh, Sarah Medland, Lucia Colodro-Conde, Kristi Krebs, Per Hoffmann, Stefan Herms, Jan Gehlen, Stephan Ripke, Swapnil Awasthi, Teemu Palviainen, Elisa M Tasanko, Roseann E Peterson, Daniel E Adkins, Andrey A Shabalin, Mark J Adams, Matthew H Iveson, Archie Campbell, Laurent F Thomas, Bendik S Winsvold, Ole Kristian Drange, Sigrid Børte, Abigail R Ter Kuile, Tan-Hoang Nguyen, Sandra M Meier, Elizabeth C Corfield, Laurie Hannigan, Daniel F Levey, Darina Czamara, Heike Weber, Karmel W Choi, Giorgio Pistis, Baptiste Couvy-Duchesne, Sandra Van der Auwera, Alexander Teumer, Robert Karlsson, Miguel Garcia-Argibay, Donghyung Lee, Rujia Wang, Ottar Bjerkeset, Eystein Stordal, Julia Bäckmann, Giovanni A Salum, Clement C Zai, James L Kennedy, Gwyneth Zai, Arun K Tiwari, Stefanie Heilmann-Heimbach, Börge Schmidt, Jaakko Kaprio, Martin M Kennedy, Joseph Boden, Alexandra Havdahl, Christel M Middeldorp, Fabiana L Lopes, Nirmala Akula, Francis J McMahon, Elisabeth B Binder, Lydia Fehm, Andreas Ströhle, Enrique Castelao, Henning Tiemeier, Dan J Stein, David Whiteman, Catherine Olsen, Zachary Fuller, Xin Wang, Naomi R Wray, Enda M Byrne, Glyn Lewis, Nicholas J Timpson, Lea K Davis, Ian B Hickie, Nathan A Gillespie, Lili Milani, Johannes Schumacher, David P Woldbye, Andreas J Forstner, Markus M Nöthen, Iiris Hovatta, John Horwood, William E Copeland, Hermine H Maes, Andrew M McIntosh, Ole A Andreassen, John-Anker Zwart, Ole Mors, Anders D Børglum, Preben B Mortensen, Helga Ask, Ted Reichborn-Kjennerud, Jackob M Najman, Murray B Stein, Joel Gelernter, Yuri Milaneschi, Brenda W Penninx, Dorret I Boomsma, Eduard Maron, Angelika Erhardt-Lehmann, Christian Rück, Tilo T Kircher, Christiane A Melzig, Georg W Alpers, Volker Arolt, Katharina Domschke, Jordan W Smoller, Martin Preisig, Nicholas G Martin, Michelle K Lupton, Annemarie I Luik, Andreas Reif, Hans J Grabe, Henrik Larsson, Patrik K Magnusson, Albertine J Oldehinkel, Catharina A Hartman, Gerome Breen, Anna R Docherty, Hilary Coon, Rupert Conrad, Kelli Lehto, Jürgen Deckert, Thalia C Eley, Manuel Mattheisen, John M Hettema
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE mice.
Angiogenesis
Authors:
Alexander Brückner, Adrian Brandtner, Sarah Rieck, Michaela Matthey, Caroline Geisen, Benedikt Fels, Marta Stei, Kristina Kusche-Vihrog, Bernd K Fleischmann, Daniela Wenzel
Irinotecan and temozolomide in combination with dasatinib and rapamycin versus irinotecan and temozolomide for patients with relapsed or refractory neuroblastoma (RIST-rNB-2011): a multicentre, open-label, randomised, controlled, phase 2 trial.
The Lancet. Oncology
Authors:
Selim Corbacioglu, Holger Lode, Susanne Ellinger, Florian Zeman, Meinolf Suttorp, Gabriele Escherich, Konrad Bochennek, Bernd Gruhn, Peter Lang, Marius Rohde, Klaus Michael Debatin, Daniel Steinbach, Andreas Beilken, Ruth Ladenstein, Rainer Spachtholz, Peter Heiss, Dirk Hellwig, Anja Tröger, Michael Koller, Karin Menhart, Markus J Riemenschneider, Saida Zoubaa, Silke Kietz, Marcus Jakob, Gunhild Sommer, Tilman Heise, Patrick Hundsdörfer, Ingrid Kühnle, Dagmar Dilloo, Stefan Schönberger, Georg Schwabe, Irene von Luettichau, Norbert Graf, Paul-Gerhardt Schlegel, Michael Frühwald, Norbert Jorch, Michael Paulussen, Dominik T Schneider, Markus Metzler, Alfred Leipold, Michaela Nathrath, Thomas Imschweiler, Holger Christiansen, Irene Schmid, Roman Crazzolara, Naghmeh Niktoreh, Gunnar Cario, Joerg Faber, Martin Demmert, Florian Babor, Birgit Fröhlich, Stefan Bielack, Toralf Bernig, Johann Greil, Angelika Eggert, Thorsten Simon, Juergen Foell
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation.
Cell
Authors:
Rainer Knoll, Elisa T Helbig, Kilian Dahm, Olufemi Bolaji, Frederik Hamm, Oliver Dietrich, Martina van Uelft, Sophie Müller, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Lev Petrov, Benjamin Krämer, Michael Kraut, Paula Stubbemann, Charlotte Thibeault, Sophia Brumhard, Heidi Theis, Gudrun Hack, Elena De Domenico, Jacob Nattermann, Matthias Becker, Marc D Beyer, David Hillus, Philipp Georg, Constantin Loers, Janina Tiedemann, Pinkus Tober-Lau, Lena Lippert, Belén Millet Pascual-Leone, Frank Tacke, Gernot Rohde, Norbert Suttorp, Martin Witzenrath, Antoine-Emmanuel Saliba, Thomas Ulas, Julia K Polansky, Birgit Sawitzki, Leif E Sander, Joachim L Schultze, Anna C Aschenbrenner, Florian Kurth
Peer-to-peer validation of Ki-67 scoring in a pathology quality circle as a tool to assess interobserver variability: are we better than we thought?
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Authors:
Marit Bernhardt, Leonie Weinhold, Christine Sanders, Oliver Hommerding, Jan-Frederic Lau, Marieta Toma, Verena Tischler, Matthias Schmid, Tomasz Zienkiewicz, Ralf Hildenbrand, Peter Gerlach, Hui Zhou, Martin Braun, Gunnar Müller, Erich Sieber, Christian Marko, Glen Kristiansen
Exploring membranous NECTIN-4 expression patterns and enfortumab vedotin response in prostate cancer.
Journal of cellular and molecular medicine
Authors:
Richard Weiten, Marit Bernhardt, Max Niemann, Glen Kristiansen, Viktor Grünwald, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Niklas Klümper, Philipp Krausewitz
Blood immune cell profiling in adults with longstanding type 1 diabetes is associated with macrovascular complications.
Frontiers in immunology
Authors:
Xuehui He, Xinhui Wang, Julia van Heck, Bram van Cranenbroek, Esther van Rijssen, Rinke Stienstra, Mihai G Netea, Irma Joosten, Cees J Tack, Hans J P M Koenen