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Publications

featured publications

  • Resolving trained immunity with systems biology.

    European journal of immunology

    Authors: Valerie A C M Koeken, Reinout van Crevel, Mihai G Netea, Yang Li

  • Prosaposin mediates inflammation in atherosclerosis.

    Science translational medicine

    Authors: Mandy M T van Leent, Thijs J Beldman, Yohana C Toner, Marnix A Lameijer, Nils Rother, Siroon Bekkering, Abraham J P Teunissen, Xianxiao Zhou, Roy van der Meel, Joost Malkus, Sheqouia A Nauta, Emma D Klein, Francois Fay, Brenda L Sanchez-Gaytan, Carlos Pérez-Medina, Ewelina Kluza, Yu-Xiang Ye, Gregory Wojtkiewicz, Edward A Fisher, Filip K Swirski, Matthias Nahrendorf, Bin Zhang, Yang Li, Bowen Zhang, Leo A B Joosten, Gerard Pasterkamp, Arjan Boltjes, Zahi A Fayad, Esther Lutgens, Mihai G Netea, Niels P Riksen, Willem J M Mulder, Raphaël Duivenvoorden

  • An open label trial of anakinra to prevent respiratory failure in COVID-19.

    eLife

    Authors: Evdoxia Kyriazopoulou, Periklis Panagopoulos, Symeon Metallidis, George N Dalekos, Garyphallia Poulakou, Nikolaos Gatselis, Eleni Karakike, Maria Saridaki, Georgia Loli, Aggelos Stefos, Danai Prasianaki, Sarah Georgiadou, Olga Tsachouridou, Vasileios Petrakis, Konstantinos Tsiakos, Maria Kosmidou, Vassiliki Lygoura, Maria Dareioti, Haralampos Milionis, Ilias C Papanikolaou, Karolina Akinosoglou, Dimitra-Melia Myrodia, Areti Gravvani, Aliki Stamou, Theologia Gkavogianni, Konstantina Katrini, Theodoros Marantos, Ioannis P Trontzas, Konstantinos Syrigos, Loukas Chatzis, Stamatios Chatzis, Nikolaos Vechlidis, Christina Avgoustou, Stamatios Chalvatzis, Miltiades Kyprianou, Jos Wm van der Meer, Jesper Eugen-Olsen, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • A modular approach toward producing nanotherapeutics targeting the innate immune system.

    Science advances

    Authors: Mandy M T van Leent, Anu E Meerwaldt, Alexandre Berchouchi, Yohana C Toner, Marianne E Burnett, Emma D Klein, Anna Vera D Verschuur, Sheqouia A Nauta, Jazz Munitz, Geoffrey Prévot, Esther M van Leeuwen, Farideh Ordikhani, Vera P Mourits, Claudia Calcagno, Philip M Robson, George Soultanidis, Thomas Reiner, Rick R M Joosten, Heiner Friedrich, Joren C Madsen, Ewelina Kluza, Roy van der Meel, Leo A B Joosten, Mihai G Netea, Jordi Ochando, Zahi A Fayad, Carlos Pérez-Medina, Willem J M Mulder, Abraham J P Teunissen

  • Data of common and species-specific transcriptional host responses to pathogenic fungi.

    Data in brief

    Authors: Mariolina Bruno, Robter Horst, Marina Pekmezovic, Vinod Kumar, Yang Li, Mihai G Netea, Jean-Paul Latgé, Mark S Gresnigt, Frank L van de Veerdonk

  • Trained Immunity: Reprogramming Innate Immunity in Health and Disease.

    Annual review of immunology

    Authors: Siroon Bekkering, Jorge Domínguez-Andrés, Leo A B Joosten, Niels P Riksen, Mihai G Netea

  • Deadly COVID-19 among the elderly: Innate immune memory helping those most in need.

    Med (New York, N.Y.)

    Authors: Yahya Sohrabi, Holger Reinecke, Leo A B Joosten, Mihai G Netea

  • induction of trained immunity in adherent human monocytes.

    STAR protocols

    Authors: Jorge Domínguez-Andrés, Rob J W Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A Blok, L Charlotte J de Bree, Mariolina Bruno, Özlem Bulut, Priya A Debisarun, Helga Dijkstra, Jéssica Cristina Dos Santos, Anaísa V Ferreira, Daniela Flores-Gomez, Laszlo A Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A C M Koeken, Heidi Lemmers, Simone J C F M Moorlag, Vera P Mourits, Jelmer H van Puffelen, Katrin Rabold, Rutger J Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P Riksen, Leo A B Joosten, Mihai G Netea

  • IL-38 prevents induction of trained immunity by inhibition of mTOR signaling.

    Journal of leukocyte biology

    Authors: Dennis M de Graaf, Lisa U Teufel, Frank L van de Veerdonk, Leo A B Joosten, Mihai G Netea, Charles A Dinarello, Rob J W Arts

  • Systemic administration of β-glucan induces immune training in microglia.

    Journal of neuroinflammation

    Authors: Yang Heng, Xiaoming Zhang, Malte Borggrewe, Hilmar R J van Weering, Maaike L Brummer, Tjalling W Nijboer, Leo A B Joosten, Mihai G Netea, Erik W G M Boddeke, Jon D Laman, Bart J L Eggen