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  • Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling.

    Nature immunology

    Authors: Flavian D Brown, Debattama R Sen, Martin W LaFleur, Jernej Godec, Veronika Lukacs-Kornek, Frank A Schildberg, Hye-Jung Kim, Kathleen B Yates, Stéphane J H Ricoult, Kevin Bi, Justin D Trombley, Varun N Kapoor, Illana A Stanley, Viviana Cremasco, Nika N Danial, Brendan D Manning, Arlene H Sharpe, W Nicholas Haining, Shannon J Turley

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  • The PNPLA3 I148M variant promotes lipid-induced hepatocyte secretion of CXC chemokines establishing a tumorigenic milieu.

    Journal of molecular medicine (Berlin, Germany)

    Authors: Hans Dieter Nischalke, Philipp Lutz, Eva Bartok, Benjamin Krämer, Bettina Langhans, Regina Frizler, Thomas Berg, Jochen Hampe, Stephan Buch, Christian Datz, Felix Stickel, Gunther Hartmann, Christian P Strassburg, Jacob Nattermann, Ulrich Spengler

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  • Genetic architecture of subcortical brain structures in 38,851 individuals.

    Nature genetics

    Authors: Claudia L Satizabal, Hieab H H Adams, Derrek P Hibar, Charles C White, Maria J Knol, Jason L Stein, Markus Scholz, Muralidharan Sargurupremraj, Neda Jahanshad, Gennady V Roshchupkin, Albert V Smith, Joshua C Bis, Xueqiu Jian, Michelle Luciano, Edith Hofer, Alexander Teumer, Sven J van der Lee, Jingyun Yang, Lisa R Yanek, Tom V Lee, Shuo Li, Yanhui Hu, Jia Yu Koh, John D Eicher, Sylvane Desrivières, Alejandro Arias-Vasquez, Ganesh Chauhan, Lavinia Athanasiu, Miguel E Rentería, Sungeun Kim, David Hoehn, Nicola J Armstrong, Qiang Chen, Avram J Holmes, Anouk den Braber, Iwona Kloszewska, Micael Andersson, Thomas Espeseth, Oliver Grimm, Lucija Abramovic, Saud Alhusaini, Yuri Milaneschi, Martina Papmeyer, Tomas Axelsson, Stefan Ehrlich, Roberto Roiz-Santiañez, Bernd Kraemer, Asta K Håberg, Hannah J Jones, G Bruce Pike, Dan J Stein, Allison Stevens, Janita Bralten, Meike W Vernooij, Tamara B Harris, Irina Filippi, A Veronica Witte, Tulio Guadalupe, Katharina Wittfeld, Thomas H Mosley, James T Becker, Nhat Trung Doan, Saskia P Hagenaars, Yasaman Saba, Gabriel Cuellar-Partida, Najaf Amin, Saima Hilal, Kwangsik Nho, Nazanin Mirza-Schreiber, Konstantinos Arfanakis, Diane M Becker, David Ames, Aaron L Goldman, Phil H Lee, Dorret I Boomsma, Simon Lovestone, Sudheer Giddaluru, Stephanie Le Hellard, Manuel Mattheisen, Marc M Bohlken, Dalia Kasperaviciute, Lianne Schmaal, Stephen M Lawrie, Ingrid Agartz, Esther Walton, Diana Tordesillas-Gutierrez, Gareth E Davies, Jean Shin, Jonathan C Ipser, Louis N Vinke, Martine Hoogman, Tianye Jia, Ralph Burkhardt, Marieke Klein, Fabrice Crivello, Deborah Janowitz, Owen Carmichael, Unn K Haukvik, Benjamin S Aribisala, Helena Schmidt, Lachlan T Strike, Ching-Yu Cheng, Shannon L Risacher, Benno Pütz, Debra A Fleischman, Amelia A Assareh, Venkata S Mattay, Randy L Buckner, Patrizia Mecocci, Anders M Dale, Sven Cichon, Marco P Boks, Mar Matarin, Brenda W J H Penninx, Vince D Calhoun, M Mallar Chakravarty, Andre F Marquand, Christine Macare, Shahrzad Kharabian Masouleh, Jaap Oosterlaan, Philippe Amouyel, Katrin Hegenscheid, Jerome I Rotter, Andrew J Schork, David C M Liewald, Greig I de Zubicaray, Tien Yin Wong, Li Shen, Philipp G Sämann, Henry Brodaty, Joshua L Roffman, Eco J C de Geus, Magda Tsolaki, Susanne Erk, Kristel R van Eijk, Gianpiero L Cavalleri, Nic J A van der Wee, Andrew M McIntosh, Randy L Gollub, Kazima B Bulayeva, Manon Bernard, Jennifer S Richards, Jayandra J Himali, Markus Loeffler, Nanda Rommelse, Wolfgang Hoffmann, Lars T Westlye, Maria C Valdés Hernández, Narelle K Hansell, Theo G M van Erp, Christiane Wolf, John B J Kwok, Bruno Vellas, Andreas Heinz, Loes M Olde Loohuis, Norman Delanty, Beng-Choon Ho, Christopher R K Ching, Elena Shumskaya, Baljeet Singh, Albert Hofman, Dennis van der Meer, Georg Homuth, Bruce M Psaty, Mark E Bastin, Grant W Montgomery, Tatiana M Foroud, Simone Reppermund, Jouke-Jan Hottenga, Andrew Simmons, Andreas Meyer-Lindenberg, Wiepke Cahn, Christopher D Whelan, Marjolein M J van Donkelaar, Qiong Yang, Norbert Hosten, Robert C Green, Anbupalam Thalamuthu, Sebastian Mohnke, Hilleke E Hulshoff Pol, Honghuang Lin, Clifford R Jack, Peter R Schofield, Thomas W Mühleisen, Pauline Maillard, Steven G Potkin, Wei Wen, Evan Fletcher, Arthur W Toga, Oliver Gruber, Matthew Huentelman, George Davey Smith, Lenore J Launer, Lars Nyberg, Erik G Jönsson, Benedicto Crespo-Facorro, Nastassja Koen, Douglas N Greve, André G Uitterlinden, Daniel R Weinberger, Vidar M Steen, Iryna O Fedko, Nynke A Groenewold, Wiro J Niessen, Roberto Toro, Christophe Tzourio, William T Longstreth, M Kamran Ikram, Jordan W Smoller, Marie-Jose van Tol, Jessika E Sussmann, Tomas Paus, Hervé Lemaître, Matthias L Schroeter, Bernard Mazoyer, Ole A Andreassen, Florian Holsboer, Chantal Depondt, Dick J Veltman, Jessica A Turner, Zdenka Pausova, Gunter Schumann, Daan van Rooij, Srdjan Djurovic, Ian J Deary, Katie L McMahon, Bertram Müller-Myhsok, Rachel M Brouwer, Hilkka Soininen, Massimo Pandolfo, Thomas H Wassink, Joshua W Cheung, Thomas Wolfers, Jean-Luc Martinot, Marcel P Zwiers, Matthias Nauck, Ingrid Melle, Nicholas G Martin, Ryota Kanai, Eric Westman, René S Kahn, Sanjay M Sisodiya, Tonya White, Arvin Saremi, Hans van Bokhoven, Han G Brunner, Henry Völzke, Margaret J Wright, Dennis van 't Ent, Markus M Nöthen, Roel A Ophoff, Jan K Buitelaar, Guillén Fernández, Perminder S Sachdev, Marcella Rietschel, Neeltje E M van Haren, Simon E Fisher, Alexa S Beiser, Clyde Francks, Andrew J Saykin, Karen A Mather, Nina Romanczuk-Seiferth, Catharina A Hartman, Anita L DeStefano, Dirk J Heslenfeld, Michael W Weiner, Henrik Walter, Pieter J Hoekstra, Paul A Nyquist, Barbara Franke, David A Bennett, Hans J Grabe, Andrew D Johnson, Christopher Chen, Cornelia M van Duijn, Oscar L Lopez, Myriam Fornage, Joanna M Wardlaw, Reinhold Schmidt, Charles DeCarli, Philip L De Jager, Arno Villringer, Stéphanie Debette, Vilmundur Gudnason, Sarah E Medland, Joshua M Shulman, Paul M Thompson, Sudha Seshadri, M Arfan Ikram

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  • FatSegNet: A fully automated deep learning pipeline for adipose tissue segmentation on abdominal dixon MRI.

    Magnetic resonance in medicine

    Authors: Santiago Estrada, Ran Lu, Sailesh Conjeti, Ximena Orozco-Ruiz, Joana Panos-Willuhn, Monique M B Breteler, Martin Reuter

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  • Sixteen-Week Physical Activity Intervention in Subjects With Increased Cardiometabolic Risk Shifts Innate Immune Function Towards a Less Proinflammatory State.

    Journal of the American Heart Association

    Authors: Marlies P Noz, Yvonne A W Hartman, Maria T E Hopman, Peter H G M Willems, Cees J Tack, Leo A B Joosten, Mihai G Netea, Dick H J Thijssen, Niels P Riksen

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  • Current gaps in sepsis immunology: new opportunities for translational research.

    The Lancet. Infectious diseases

    Authors: Ignacio Rubio, Marcin F Osuchowski, Manu Shankar-Hari, Tomasz Skirecki, Martin Sebastian Winkler, Gunnar Lachmann, Paul La Rosée, Guillaume Monneret, Fabienne Venet, Michael Bauer, Frank M Brunkhorst, Matthijs Kox, Jean-Marc Cavaillon, Florian Uhle, Markus A Weigand, Stefanie B Flohé, W Joost Wiersinga, Marta Martin-Fernandez, Raquel Almansa, Ignacio Martin-Loeches, Antoni Torres, Evangelos J Giamarellos-Bourboulis, Massimo Girardis, Andrea Cossarizza, Mihai G Netea, Tom van der Poll, André Scherag, Christian Meisel, Joerg C Schefold, Jesús F Bermejo-Martín

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  • NFAT primes the human RORC locus for RORγt expression in CD4 T cells.

    Nature communications

    Authors: Hanane Yahia-Cherbal, Magda Rybczynska, Domenica Lovecchio, Tharshana Stephen, Chloé Lescale, Katarzyna Placek, Jérome Larghero, Lars Rogge, Elisabetta Bianchi

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  • Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium.

    Scientific reports

    Authors: Jose M Sánchez-Maldonado, Rafael Cáliz, Luz Canet, Rob Ter Horst, Olivier Bakker, Alfons A den Broeder, Manuel Martínez-Bueno, Helena Canhão, Ana Rodríguez-Ramos, Carmen B Lupiañez, María José Soto-Pino, Antonio García, Eva Pérez-Pampin, Alfonso González-Utrilla, Alejandro Escudero, Juana Segura-Catena, Romana T Netea-Maier, Miguel Ángel Ferrer, Eduardo Collantes-Estevez, Miguel Ángel López Nevot, Yang Li, Manuel Jurado, João E Fonseca, Mihai G Netea, Marieke J H Coenen, Juan Sainz

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  • DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients' survival, immune cell infiltrates, mutational load, and interferon γ signature.

    EBioMedicine

    Authors: Verena Sailer, Ulrike Sailer, Emma Grace Bawden, Romina Zarbl, Constanze Wiek, Timo J Vogt, Joern Dietrich, Sophia Loick, Ingela Grünwald, Marieta Toma, Carsten Golletz, Andreas Gerstner, Glen Kristiansen, Friedrich Bootz, Kathrin Scheckenbach, Jennifer Landsberg, Dimo Dietrich

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  • Multiplexed and single cell tracing of lipid metabolism.

    Nature methods

    Authors: Christoph Thiele, Klaus Wunderling, Philipp Leyendecker

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