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featured publications

  • Cerebrospinal fluid IL-1β is elevated in tuberculous meningitis patients but not associated with mortality.

    Tuberculosis (Edinburgh, Scotland)

    Authors: Valerie A C M Koeken, Ahmad R Ganiem, Sofiati Dian, Rovina Ruslami, Lidya Chaidir, Mihai G Netea, Vinod Kumar, Bachti Alisjahbana, Reinout van Crevel, Arjan van Laarhoven

  • Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons.

    Cell reports. Medicine

    Authors: Nils Rother, Cansu Yanginlar, Rik G H Lindeboom, Siroon Bekkering, Mandy M T van Leent, Baranca Buijsers, Inge Jonkman, Mark de Graaf, Marijke Baltissen, Lieke A Lamers, Niels P Riksen, Zahi A Fayad, Willem J M Mulder, Luuk B Hilbrands, Leo A B Joosten, Mihai G Netea, Michiel Vermeulen, Johan van der Vlag, Raphaël Duivenvoorden

  • Immune defects in patients with pulmonary disease without cystic fibrosis.

    ERJ open research

    Authors: Milou M F Schuurbiers, Mariolina Bruno, Sanne M H Zweijpfenning, Cecile Magis-Escurra, Martin Boeree, Mihai G Netea, Jakko van Ingen, Frank van de Veerdonk, Wouter Hoefsloot

  • Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease.

    eLife

    Authors: Marlies P Noz, Siroon Bekkering, Laszlo Groh, Tim Mj Nielen, Evert Jp Lamfers, Andreas Schlitzer, Saloua El Messaoudi, Niels van Royen, Erik Hjpg Huys, Frank Wmb Preijers, Esther Mm Smeets, Erik Hjg Aarntzen, Bowen Zhang, Yang Li, Manita Ej Bremmers, Walter Jfm van der Velden, Harry Dolstra, Leo Ab Joosten, Marc E Gomes, Mihai G Netea, Niels P Riksen

  • Top publication

    CRELD1 modulates homeostasis of the immune system in mice and humans.

    Nature immunology

    Authors: Lorenzo Bonaguro, Maren Köhne, Lisa Schmidleithner, Jonas Schulte-Schrepping, Stefanie Warnat-Herresthal, Arik Horne, Paul Kern, Patrick Günther, Rob Ter Horst, Martin Jaeger, Souad Rahmouni, Michel Georges, Christine S Falk, Yang Li, Elvira Mass, Marc Beyer, Leo A B Joosten, Mihai G Netea, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner

  • Trained Immunity Confers Broad-Spectrum Protection Against Bacterial Infections.

    The Journal of infectious diseases

    Authors: Eleonora Ciarlo, Tytti Heinonen, Charlotte Théroude, Fatemeh Asgari, Didier Le Roy, Mihai G Netea, Thierry Roger

  • Trained Immunity in Atherosclerotic Cardiovascular Disease.

    Arteriosclerosis, thrombosis, and vascular biology

    Authors: Daniela Flores-Gomez, Siroon Bekkering, Mihai G Netea, Niels P Riksen

  • Recent Common Origin, Reduced Population Size, and Marked Admixture Have Shaped European Roma Genomes.

    Molecular biology and evolution

    Authors: Erica Bianco, Guillaume Laval, Neus Font-Porterias, Carla García-Fernández, Begoña Dobon, Rubén Sabido-Vera, Emilija Sukarova Stefanovska, Vaidutis Kučinskas, Halyna Makukh, Horolma Pamjav, Lluis Quintana-Murci, Mihai G Netea, Jaume Bertranpetit, Francesc Calafell, David Comas

  • Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition.

    Cell

    Authors: Bram Priem, Mandy M T van Leent, Abraham J P Teunissen, Alexandros Marios Sofias, Vera P Mourits, Lisa Willemsen, Emma D Klein, Roderick S Oosterwijk, Anu E Meerwaldt, Jazz Munitz, Geoffrey Prévot, Anna Vera Verschuur, Sheqouia A Nauta, Esther M van Leeuwen, Elizabeth L Fisher, Karen A M de Jong, Yiming Zhao, Yohana C Toner, Georgios Soultanidis, Claudia Calcagno, Paul H H Bomans, Heiner Friedrich, Nico Sommerdijk, Thomas Reiner, Raphaël Duivenvoorden, Eva Zupančič, Julie S Di Martino, Ewelina Kluza, Mohammad Rashidian, Hidde L Ploegh, Rick M Dijkhuizen, Sjoerd Hak, Carlos Pérez-Medina, Jose Javier Bravo-Cordero, Menno P J de Winther, Leo A B Joosten, Andrea van Elsas, Zahi A Fayad, Alexander Rialdi, Denis Torre, Ernesto Guccione, Jordi Ochando, Mihai G Netea, Arjan W Griffioen, Willem J M Mulder

  • Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.

    Cell

    Authors: Lydia Kalafati, Ioannis Kourtzelis, Jonas Schulte-Schrepping, Xiaofei Li, Aikaterini Hatzioannou, Tatyana Grinenko, Eman Hagag, Anupam Sinha, Canan Has, Sevina Dietz, Antonio Miguel de Jesus Domingues, Marina Nati, Sundary Sormendi, Ales Neuwirth, Antonios Chatzigeorgiou, Athanasios Ziogas, Mathias Lesche, Andreas Dahl, Ian Henry, Pallavi Subramanian, Ben Wielockx, Peter Murray, Peter Mirtschink, Kyoung-Jin Chung, Joachim L Schultze, Mihai G Netea, George Hajishengallis, Panayotis Verginis, Ioannis Mitroulis, Triantafyllos Chavakis