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  • Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.

    Nature cell biology

    Authors: Camilla Salvagno, Metamia Ciampricotti, Sander Tuit, Cheei-Sing Hau, Antoinette van Weverwijk, Seth B Coffelt, Kelly Kersten, Kim Vrijland, Kevin Kos, Thomas Ulas, Ji-Ying Song, Chia-Huey Ooi, Dominik Rüttinger, Philippe A Cassier, Jos Jonkers, Joachim L Schultze, Carola H Ries, Karin E de Visser

  • Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.

    Kidney international

    Authors: Victor G Puelles, David Fleck, Lena Ortz, Stella Papadouri, Thiago Strieder, Alexander M C Böhner, James W van der Wolde, Michael Vogt, Turgay Saritas, Christoph Kuppe, Astrid Fuss, Sylvia Menzel, Barbara M Klinkhammer, Gerhard Müller-Newen, Felix Heymann, Leon Decker, Fabian Braun, Oliver Kretz, Tobias B Huber, Etsuo A Susaki, Hiroki R Ueda, Peter Boor, Jürgen Floege, Rafael Kramann, Christian Kurts, John F Bertram, Marc Spehr, David J Nikolic-Paterson, Marcus J Moeller

  • LipidII interaction with specific residues of Mycobacterium tuberculosis PknB extracytoplasmic domain governs its optimal activation.

    Nature communications

    Authors: Prabhjot Kaur, Marvin Rausch, Basanti Malakar, Uchenna Watson, Nikhil P Damle, Yogesh Chawla, Sandhya Srinivasan, Kanika Sharma, Tanja Schneider, Gagan Deep Jhingan, Deepak Saini, Debasisa Mohanty, Fabian Grein, Vinay Kumar Nandicoori

  • Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.

    Science (New York, N.Y.)

    Authors: Svetoslav Chakarov, Hwee Ying Lim, Leonard Tan, Sheau Yng Lim, Peter See, Josephine Lum, Xiao-Meng Zhang, Shihui Foo, Satoshi Nakamizo, Kaibo Duan, Wan Ting Kong, Rebecca Gentek, Akhila Balachander, Daniel Carbajo, Camille Bleriot, Benoit Malleret, John Kit Chung Tam, Sonia Baig, Muhammad Shabeer, Sue-Anne Ee Shiow Toh, Andreas Schlitzer, Anis Larbi, Thomas Marichal, Bernard Malissen, Jinmiao Chen, Michael Poidinger, Kenji Kabashima, Marc Bajenoff, Lai Guan Ng, Veronique Angeli, Florent Ginhoux

  • Preliminary results of biodistribution and dosimetric analysis of [Ga]Ga-DOTA: a new zoledronate-based bisphosphonate for PET/CT diagnosis of bone diseases.

    Annals of nuclear medicine

    Authors: Ambreen Khawar, Elisabeth Eppard, Frank Roesch, Hojjat Ahmadzadehfar, Stefan Kürpig, Michael Meisenheimer, Florian C Gaertner, Markus Essler, Ralph A Bundschuh

  • Diagnosis of peri-prosthetic loosening of total hip and knee arthroplasty using F-Fluoride PET/CT.

    Oncotarget

    Authors: Sebastian Koob, Florian C Gaertner, Tom Rainer Jansen, Jan Schmolders, Sascha Gravius, Holger Strunk, Dieter Christian Wirtz, Markus Essler

  • Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice.

    Scientific reports

    Authors: Kathrin Thiem, Geerte Hoeke, Susan van den Berg, Anneke Hijmans, Cor W M Jacobs, Enchen Zhou, Isabel M Mol, Maria Mouktaroudi, Johan Bussink, Thirumala D Kanneganti, Esther Lutgens, Rinke Stienstra, Cees J Tack, Mihai G Netea, Patrick C N Rensen, Jimmy F P Berbée, Janna A van Diepen

  • Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes.

    Nature communications

    Authors: Marlijn van der Poel, Thomas Ulas, Mark R Mizee, Cheng-Chih Hsiao, Suzanne S M Miedema, Adelia, Karianne G Schuurman, Boy Helder, Sander W Tas, Joachim L Schultze, Jörg Hamann, Inge Huitinga

  • Preclinical development of an oral anti- macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

    Science translational medicine

    Authors: Mark J Taylor, Thomas W von Geldern, Louise Ford, Marc P Hübner, Kennan Marsh, Kelly L Johnston, Hanna T Sjoberg, Sabine Specht, Nicolas Pionnier, Hayley E Tyrer, Rachel H Clare, Darren A N Cook, Emma Murphy, Andrew Steven, John Archer, Dominique Bloemker, Franziska Lenz, Marianne Koschel, Alexandra Ehrens, Haelly M Metuge, Valerinne C Chunda, Patrick W Ndongmo Chounna, Abdel J Njouendou, Fanny F Fombad, Robert Carr, Howard E Morton, Ghaith Aljayyoussi, Achim Hoerauf, Samuel Wanji, Dale J Kempf, Joseph D Turner, Stephen A Ward

  • Brief report - Telomere length is a poor biomarker to predict 1-year mortality or cardiovascular comorbidity in patients with transcatheter aortic valve replacement.

    PloS one

    Authors: Martin Steinmetz, Charlotte Schmitter, Tobias Radecke, Anja Stundl, Georg Nickenig, Christian Schaefer, Nadjib Schahab, Mariuca Vasa-Nicotera, Jan-Malte Sinning