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featured publications

  • High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing.

    Nature protocols

    Authors: Brett J Hilton, Oriane Blanquie, Andrea Tedeschi, Frank Bradke

  • Fueling Type I Interferonopathies: Regulation and Function of Type I Interferon Antiviral Responses.

    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research

    Authors: Chen Seng Ng, Hiroki Kato, Takashi Fujita

  • Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.

    Cell chemical biology

    Authors: Calla M Olson, Yanke Liang, Alan Leggett, Woojun D Park, Lianbo Li, Caitlin E Mills, Selma Z Elsarrag, Scott B Ficarro, Tinghu Zhang, Robert Düster, Matthias Geyer, Taebo Sim, Jarrod A Marto, Peter K Sorger, Ken D Westover, Charles Y Lin, Nicholas Kwiatkowski, Nathanael S Gray

  • Coagulation Factor XIIIa Inhibitor Tridegin: On the Role of Disulfide Bonds for Folding, Stability, and Function.

    Journal of medicinal chemistry

    Authors: Charlotte A Bäuml, Thomas Schmitz, Ajay Abisheck Paul George, Monica Sudarsanam, Kornelia Hardes, Torsten Steinmetzer, Lori A Holle, Alisa S Wolberg, Bernd Pötzsch, Johannes Oldenburg, Arijit Biswas, Diana Imhof

  • The Discovery of a LEMD2-Associated Nuclear Envelopathy with Early Progeroid Appearance Suggests Advanced Applications for AI-Driven Facial Phenotyping.

    American journal of human genetics

    Authors: Felix Marbach, Cecilie F Rustad, Angelika Riess, Dejan Đukić, Tzung-Chien Hsieh, Itamar Jobani, Trine Prescott, Andrea Bevot, Florian Erger, Gunnar Houge, Maria Redfors, Janine Altmueller, Tomasz Stokowy, Christian Gilissen, Christian Kubisch, Emanuela Scarano, Laura Mazzanti, Torunn Fiskerstrand, Peter M Krawitz, Davor Lessel, Christian Netzer

  • Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis.

    EBioMedicine

    Authors: Yvonn Heun, Joachim Pircher, Thomas Czermak, Philipp Bluem, Georg Hupel, Monica Bohmer, Bjoern F Kraemer, Kristin Pogoda, Alexander Pfeifer, Markus Woernle, Andrea Ribeiro, Max Hübner, Simone Kreth, Ralf A Claus, Sebastian Weis, Luisa Ungelenk, Florian Krötz, Ulrich Pohl, Hanna Mannell

  • The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity.

    Scientific reports

    Authors: João M Monteiro, Gonçalo Covas, Daniela Rausch, Sérgio R Filipe, Tanja Schneider, Hans-Georg Sahl, Mariana G Pinho

  • Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model.

    Scientific reports

    Authors: Laia Civit, Ioanna Theodorou, Franziska Frey, Holger Weber, Andreas Lingnau, Carsten Gröber, Michael Blank, Chloé Dambrune, James Stunden, Marc Beyer, Joachim Schultze, Eicke Latz, Frédéric Ducongé, Michael H G Kubbutat, Günter Mayer

  • The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

    Molecular psychiatry

    Authors: Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez, Tammie Benzinger, Alison Goate, Celeste M Karch, Anne M Fagan, Eric McDade, Katharina Buerger, Johannes Levin, Marco Duering, Martin Dichgans, Marc Suárez-Calvet, Christian Haass, Brian A Gordon, Yen Ying Lim, Colin L Masters, Daniel Janowitz, Cihan Catak, Steffen Wolfsgruber, Michael Wagner, Esther Milz, Sonia Moreno-Grau, Stefan Teipel, Michel J Grothe, Ingo Kilimann, Martin Rossor, Nick Fox, Christoph Laske, Jasmeer Chhatwal, Peter Falkai, Robert Perneczky, Jae-Hong Lee, Annika Spottke, Henning Boecker, Frederic Brosseron, Klaus Fliessbach, Michael T Heneka, Peter Nestor, Oliver Peters, Manuel Fuentes, Felix Menne, Josef Priller, Eike J Spruth, Christiana Franke, Anja Schneider, Christine Westerteicher, Oliver Speck, Jens Wiltfang, Claudia Bartels, Miguel Ángel Araque Caballero, Coraline Metzger, Daniel Bittner, Stephen Salloway, Adrian Danek, Jason Hassenstab, Igor Yakushev, Peter R Schofield, John C Morris, Randall J Bateman, Michael Ewers

  • Optogenetic stimulation of G-signaling in the heart with high spatio-temporal precision.

    Nature communications

    Authors: Philipp Makowka, Tobias Bruegmann, Vanessa Dusend, Daniela Malan, Thomas Beiert, Michael Hesse, Bernd K Fleischmann, Philipp Sasse