Preclinical evidence for the use of anti-Trop-2 antibody-drug conjugate Sacituzumab govitecan in cerebral metastasized castration-resistant prostate cancer.
Cancer medicine
Authors:
Richard Weiten, Max Niemann, Eduard Below, Lea L Friker, Damian J Ralser, Marieta Toma, Glen Kristiansen, Oliver Hahn, Sabrina Zechel, Viktor Grünwald, Tobias Bald, Johannes Siewert, Torsten Pietsch, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Philipp Krausewitz, Niklas Klümper
Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss.
Cell
Authors:
Hui Wang, Kimon Divaris, Bohu Pan, Xiaofei Li, Jong-Hyung Lim, Gundappa Saha, Marko Barovic, Danai Giannakou, Jonathan M Korostoff, Yu Bing, Souvik Sen, Kevin Moss, Di Wu, James D Beck, Christie M Ballantyne, Pradeep Natarajan, Kari E North, Mihai G Netea, Triantafyllos Chavakis, George Hajishengallis
Authors:
Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Alexander Bartelt, Hülya Bayir, Christina M Bebber, Kivanc Birsoy, Jan P Böttcher, Simone Brabletz, Thomas Brabletz, Ashley R Brown, Bernhard Brüne, Giorgia Bulli, Alix Bruneau, Quan Chen, Gina M DeNicola, Tobias P Dick, Ayelén Distéfano, Scott J Dixon, Jan B Engler, Julia Esser-von Bieren, Maria Fedorova, José Pedro Friedmann Angeli, Manuel A Friese, Dominic C Fuhrmann, Ana J García-Sáez, Karolina Garbowicz, Magdalena Götz, Wei Gu, Linda Hammerich, Behrouz Hassannia, Xuejun Jiang, Aicha Jeridi, Yun Pyo Kang, Valerian E Kagan, David B Konrad, Stefan Kotschi, Peng Lei, Marlène Le Tertre, Sima Lev, Deguang Liang, Andreas Linkermann, Carolin Lohr, Svenja Lorenz, Tom Luedde, Axel Methner, Bernhard Michalke, Anna V Milton, Junxia Min, Eikan Mishima, Sebastian Müller, Hozumi Motohashi, Martina U Muckenthaler, Shohei Murakami, James A Olzmann, Gabriela Pagnussat, Zijan Pan, Thales Papagiannakopoulos, Lohans Pedrera Puentes, Derek A Pratt, Bettina Proneth, Lukas Ramsauer, Raphael Rodriguez, Yoshiro Saito, Felix Schmidt, Carina Schmitt, Almut Schulze, Annemarie Schwab, Anna Schwantes, Mariluz Soula, Benedikt Spitzlberger, Brent R Stockwell, Leonie Thewes, Oliver Thorn-Seshold, Shinya Toyokuni, Wulf Tonnus, Andreas Trumpp, Peter Vandenabeele, Tom Vanden Berghe, Vivek Venkataramani, Felix C E Vogel, Silvia von Karstedt, Fudi Wang, Frank Westermann, Chantal Wientjens, Christoph Wilhelm, Michele Wölk, Katherine Wu, Xin Yang, Fan Yu, Yilong Zou, Marcus Conrad
Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel disease.
Molecular psychiatry
Authors:
Quentin Le Grand, Ami Tsuchida, Alexandra Koch, Mohammed-Aslam Imtiaz, N Ahmad Aziz, Chloé Vigneron, Laure Zago, Mark Lathrop, Alexandre Dubrac, Thierry Couffinhal, Fabrice Crivello, Paul M Matthews, Aniket Mishra, Monique M B Breteler, Christophe Tzourio, Stéphanie Debette
Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.
Molecular metabolism
Authors:
Frederike J Graelmann, Fabian Gondorf, Yasmin Majlesain, Birte Niemann, Katarina Klepac, Dominic Gosejacob, Marlene Gottschalk, Michelle Mayer, Irina Iriady, Philip Hatzfeld, Sophie K Lindenberg, Klaus Wunderling, Christoph Thiele, Zeinab Abdullah, Wei He, Karsten Hiller, Kristian Händler, Marc D Beyer, Thomas Ulas, Alexander Pfeifer, Charlotte Esser, Heike Weighardt, Irmgard Förster, Laia Reverte-Salisa
Associations of Urine and Plasma Metabolites with Kidney Failure and Death in a CKD Cohort.
American journal of kidney diseases : the official journal of the National Kidney Foundation
Authors:
Inga Steinbrenner, Ulla T Schultheiss, Helena Bächle, Yurong Cheng, Charlotte Behning, Matthias Schmid, Wan-Jin Yeo, Bing Yu, Morgan E Grams, Pascal Schlosser, Helena Stockmann, Wolfram Gronwald, Peter J Oefner, Elke Schaeffner, Kai-Uwe Eckardt, Anna Köttgen, Peggy Sekula
Evolution of protective SARS-CoV-2-specific B and T cell responses upon vaccination and Omicron breakthrough infection.
iScience
Authors:
Mohamed I M Ahmed, Sebastian Einhauser, Clemens Peiter, Antonia Senninger, Olga Baranov, Tabea M Eser, Manuel Huth, Laura Olbrich, Noemi Castelletti, Raquel Rubio-Acero, George Carnell, Jonathan Heeney, Inge Kroidl, Kathrin Held, Andreas Wieser, Christian Janke, Michael Hoelscher, Jan Hasenauer, Ralf Wagner, Christof Geldmacher
L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial.
Nature communications
Authors:
Frank A Giordano, Julian P Layer, Sonia Leonardelli, Lea L Friker, Roberta Turiello, Dillon Corvino, Thomas Zeyen, Christina Schaub, Wolf Müller, Elena Sperk, Leonard Christopher Schmeel, Katharina Sahm, Christoph Oster, Sied Kebir, Peter Hambsch, Torsten Pietsch, Sotirios Bisdas, Michael Platten, Martin Glas, Clemens Seidel, Ulrich Herrlinger, Michael Hölzel