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  • Top publication

    Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.

    The Journal of experimental medicine

    Authors: Nina Kessler, Susanne F Viehmann, Calvin Krollmann, Karola Mai, Katharina M Kirschner, Hella Luksch, Prasanti Kotagiri, Alexander M C Böhner, Dennis Huugen, Carina C de Oliveira Mann, Simon Otten, Stefanie A I Weiss, Thomas Zillinger, Kristiyana Dobrikova, Dieter E Jenne, Rayk Behrendt, Andrea Ablasser, Eva Bartok, Gunther Hartmann, Karl-Peter Hopfner, Paul A Lyons, Peter Boor, Angela Rösen-Wolff, Lino L Teichmann, Peter Heeringa, Christian Kurts, Natalio Garbi

  • Induction of Interferon-Stimulated Genes Correlates with Reduced Growth of Influenza A Virus in Lungs after RIG-I Agonist Treatment of Ferrets.

    Journal of virology

    Authors: Lara S U Schwab, Sarah L Londrigan, Andrew G Brooks, Aeron C Hurt, Anshupa Sahu, Yi-Mo Deng, Jean Moselen, Christoph Coch, Thomas Zillinger, Gunther Hartmann, Patrick C Reading

  • Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection.

    Viruses

    Authors: Lara S U Schwab, Fernando Villalón-Letelier, Melkamu B Tessema, Sarah L Londrigan, Andrew G Brooks, Aeron Hurt, Christoph Coch, Thomas Zillinger, Gunther Hartmann, Patrick C Reading

  • Human Beta Papillomavirus Type 8 E1 and E2 Proteins Suppress the Activation of the RIG-I-Like Receptor MDA5.

    Viruses

    Authors: Stephanie Rattay, Martin Hufbauer, Christian Hagen, Bastian Putschli, Christoph Coch, Baki Akgül, Gunther Hartmann

  • Influence on study outcomes of an inpatient study by the behavior of the study staff (PINgPOng): study protocol for a randomized clinical trial.

    Trials

    Authors: Martin Coenen, Ulrike Bingel, Matthias Zunhammer, Maria Soledad Berdaguer, Christine Fuhrmann, Rolf Fimmers, Jens Rengelshausen, Gunther Hartmann, Manfred Schedlowski, Christoph Coch

  • Diagnostic Potential of Exosomal microRNAs in Colorectal Cancer.

    Diagnostics (Basel, Switzerland)

    Authors: Jonas Dohmen, Alexander Semaan, Makbule Kobilay, Martin Zaleski, Vittorio Branchi, Anja Schlierf, Karina Hettwer, Steffen Uhlig, Gunther Hartmann, Jörg C Kalff, Hanno Matthaei, Philipp Lingohr, Stefan Holdenrieder

  • Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity.

    Journal for immunotherapy of cancer

    Authors: Beatrice Thier, Fang Zhao, Simone Stupia, Alicia Brüggemann, Johannes Koch, Nina Schulze, Susanne Horn, Christoph Coch, Gunther Hartmann, Antje Sucker, Dirk Schadendorf, Annette Paschen

  • Deficiency in coatomer complex I causes aberrant activation of STING signalling.

    Nature communications

    Authors: Annemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, Chien-Hsiung Yu, Pawat Laohamonthonkul, Cassandra R Harapas, Ronnie Ren Jie Low, Dominic De Nardo, Laura F Dagley, Michael J Mlodzianoski, Kelly L Rogers, Thomas Zillinger, Gunther Hartmann, Michael P Gantier, Marco Gattorno, Matthias Geyer, Stefano Volpi, Sophia Davidson, Seth L Masters

  • RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection.

    Molecular therapy. Nucleic acids

    Authors: Samira Marx, Beate M Kümmerer, Christian Grützner, Hiroki Kato, Martin Schlee, Marcel Renn, Eva Bartok, Gunther Hartmann

  • Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus.

    Journal of clinical immunology

    Authors: Annemarie Steiner, Thomas Reygaerts, Alessandra Pontillo, Isabella Ceccherini, Jonas Moecking, Fiona Moghaddas, Sophia Davidson, Francesco Caroli, Alice Grossi, Fabio Fernandes Morato Castro, Jorge Kalil, Florian N Gohr, Florian I Schmidt, Eva Bartok, Thomas Zillinger, Gunther Hartmann, Matthias Geyer, Marco Gattorno, Leonardo Oliveira Mendonça, Seth L Masters