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  • Soluble urate-induced effects on cytokine production in vitro - Assessment of methodologies and cell types.

    Cytokine

    Authors: Ruiqi Liu, Viola Klück, Brenda Kischkel, Helin Tercan, Mihai G Netea, Tania O Crişan, Leo A B Joosten

  • The effector program of human CD8 T cells supports tissue remodeling.

    The Journal of experimental medicine

    Authors: Michael Delacher, Lisa Schmidleithner, Malte Simon, Philipp Stüve, Lieke Sanderink, Agnes Hotz-Wagenblatt, Marina Wuttke, Kathrin Schambeck, Brigitte Ruhland, Veronika Hofmann, Sebastian Bittner, Uwe Ritter, Asmita Pant, Sara Salome Helbich, Morten Voss, Niels A Lemmermann, Lisa Bessiri-Schake, Toszka Bohn, Andreas Eigenberger, Ayse Nur Menevse, Claudia Gebhard, Nicholas Strieder, Hinrich Abken, Michael Rehli, Jochen Huehn, Philipp Beckhove, Thomas Hehlgans, Henrik Junger, Edward K Geissler, Lukas Prantl, Jens M Werner, Christian Schmidl, Benedikt Brors, Charles D Imbusch, Markus Feuerer

  • Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation.

    Clinical epigenetics

    Authors: Laura K Godfrey, Jan Forster, Sven-Thorsten Liffers, Christopher Schröder, Johannes Köster, Leonie Henschel, Kerstin U Ludwig, David Lähnemann, Marija Trajkovic-Arsic, Diana Behrens, Aldo Scarpa, Rita T Lawlor, Kathrin E Witzke, Barbara Sitek, Steven A Johnsen, Sven Rahmann, Bernhard Horsthemke, Michael Zeschnigk, Jens T Siveke

  • Hypermethylated SHOX2 in circulating cell-free DNA post renal cell carcinoma surgery as TNM-independent biomarker for recurrence risk.

    American journal of translational research

    Authors: Thomas Büttner, Romina Zarbl, Philipp Krausewitz, Sebastian Strieth, Glen Kristiansen, Markus Eckstein, Damian J Ralser, Michael Hölzel, Manuel Ritter, Jörg Ellinger, Dimo Dietrich, Niklas Klümper

  • First-Line Treatment for Advanced Hepatocellular Carcinoma: A Three-Armed Real-World Comparison.

    Journal of hepatocellular carcinoma

    Authors: Robert Mahn, Oscar André Glüer, Farsaneh Sadeghlar, Christian Möhring, Taotao Zhou, Thomas Anhalt, Malte Benedikt Monin, Alexander Kania, Tim R Glowka, Georg Feldmann, Peter Brossart, Joerg C Kalff, Ingo G H Schmidt-Wolf, Christian P Strassburg, Maria A Gonzalez-Carmona

  • Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed.

    Infectious diseases of poverty

    Authors: Robert Colebunders, Joseph Nelson Siewe Fodjo, Olivia Kamoen, Luís-Jorge Amaral, Amber Hadermann, Chiara Trevisan, Mark J Taylor, Julia Gauglitz, Achim Hoerauf, Yasuaki Sato, Katja Polman, María-Gloria Basáñez, Dan Bhwana, Thomson Lakwo, Gasim Abd-Elfarag, Sébastien D Pion

  • Association Between Clonal Hematopoiesis Driver Mutations, Immune Cell Function, and the Vasculometabolic Complications of Obesity.

    Journal of the American Heart Association

    Authors: Helin Tercan, Benjamin C Cossins, Rosanne C van Deuren, Joost H W Rutten, Leo A B Joosten, Mihai G Netea, Alexander Hoischen, Siroon Bekkering, Niels P Riksen

  • Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition.

    Molecular psychiatry

    Authors: Dayana Hayek, Gabriel Ziegler, Luca Kleineidam, Frederic Brosseron, Aditya Nemali, Niklas Vockert, Kishore A Ravichandran, Matthew J Betts, Oliver Peters, Luisa-Sophie Schneider, Xiao Wang, Josef Priller, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Claudia Bartels, Ayda Rostamzadeh, Wenzel Glanz, Katharina Buerger, Daniel Janowitz, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Christoph Laske, David Mengel, Matthis Synofzik, Matthias H Munk, Annika Spottke, Nina Roy, Sandra Roeske, Elizabeth Kuhn, Alfredo Ramirez, Laura Dobisch, Matthias Schmid, Moritz Berger, Steffen Wolfsgruber, Renat Yakupov, Stefan Hetzer, Peter Dechent, Michael Ewers, Klaus Scheffler, Björn H Schott, Stefanie Schreiber, Adelina Orellana, Itziar de Rojas, Marta Marquié, Mercè Boada, Oscar Sotolongo, Pablo García González, Raquel Puerta, Emrah Düzel, Frank Jessen, Michael Wagner, Augustín Ruiz, Michael T Heneka, Anne Maass

  • UNC93B1 variants underlie TLR7-dependent autoimmunity.

    Science immunology

    Authors: Christine Wolf, Ee Lyn Lim, Mohammad Mokhtari, Barbara Kind, Alexandru Odainic, Eusebia Lara-Villacanas, Sarah Koss, Simon Mages, Katharina Menzel, Kerstin Engel, Gregor Dückers, Benedikt Bernbeck, Dominik T Schneider, Kathrin Siepermann, Tim Niehues, Carl Christoph Goetzke, Pawel Durek, Kirsten Minden, Thomas Dörner, Anna Stittrich, Franziska Szelinski, Gabriela Maria Guerra, Mona Massoud, Markus Bieringer, Carina C de Oliveira Mann, Eduardo Beltrán, Tilmann Kallinich, Mir-Farzin Mashreghi, Susanne V Schmidt, Eicke Latz, Johanna Klughammer, Olivia Majer, Min Ae Lee-Kirsch

  • Intermediate monocytes are associated with the first major adverse cardiovascular event in patients with stable coronary artery disease.

    International journal of cardiology

    Authors: Mihaela I Dregoesc, Adrian B Țigu, Siroon Bekkering, Charlotte D C C van der Heijden, Laura Rodwell, Sorana D Bolboacă, Leo A B Joosten, Mihai G Netea, Niels P Riksen, Adrian C Iancu