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  • Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP.

    Nature communications

    Authors: Martin F Peter, Jan A Ruland, Yeojin Kim, Philipp Hendricks, Niels Schneberger, Jan Peter Siebrasse, Gavin H Thomas, Ulrich Kubitscheck, Gregor Hagelueken

  • DNA damage signaling in macrophages modulates systemic cytokine levels in response to oxidative stress.

    eLife

    Authors: Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

  • Treatment of atopic dermatitis: Recently approved drugs and advanced clinical development programs.

    Allergy

    Authors: Svenja Müller, Laura Maintz, Thomas Bieber

  • TMPRSS2 isoform 1 downregulation by G-quadruplex stabilization induces SARS-CoV-2 replication arrest.

    BMC biology

    Authors: Alessio De Magis, Philipp Schult, Antonia Schönleber, Rebecca Linke, Kerstin U Ludwig, Beate M Kümmerer, Katrin Paeschke

  • The mitochondrial protease PARL is required for spermatogenesis.

    Communications biology

    Authors: Sarah Schumacher, Laura Klose, Jessica Lambertz, Dieter Lütjohann, Ronald Biemann, Stefanie Kuerten, Lars Fester

  • Hepatobiliary manifestations in patients with ulcerative colitis: a retrospective analysis.

    Frontiers in medicine

    Authors: Katharina Stratmann, Songül Aydolmus, Wenyi Gu, Dominik Heling, Ulrich Spengler, Birgit Terjung, Christian P Strassburg, Richard Vollenberg, Irina Blumenstein, Jonel Trebicka

  • Adipocyte precursor-derived NRG1 promotes resistance to FGFR inhibition in urothelial carcinoma.

    Cancer research

    Authors: Sana Hosni, Viola Kilian, Niklas Klümper, Daniela Gabbia, Katharina Sieckmann, Dillon Corvino, Anja Winkler, Miriam Saponaro, Karin Woersdoerfer, Doris Schmidt, Oliver Hahn, Ilaria Zanotto, Marina Bertlich, Marieta Toma, Tobias Bald, Markus Eckstein, Michael Hölzel, Matthias Geyer, Manuel Ritter, Dagmar Wachten, Sara De Martin, Abdullah Alajati

  • Host genetic regulation of human gut microbial structural variation.

    Nature

    Authors: Daria V Zhernakova, Daoming Wang, Lei Liu, Sergio Andreu-Sánchez, Yue Zhang, Angel J Ruiz-Moreno, Haoran Peng, Niels Plomp, Ángela Del Castillo-Izquierdo, Ranko Gacesa, Esteban A Lopera-Maya, Godfrey S Temba, Vesla I Kullaya, Sander S van Leeuwen, Ramnik J Xavier, Quirijn de Mast, Leo A B Joosten, Niels P Riksen, Joost H W Rutten, Mihai G Netea, Serena Sanna, Cisca Wijmenga, Rinse K Weersma, Alexandra Zhernakova, Hermie J M Harmsen, Jingyuan Fu

  • The pathophysiology of sepsis and precision-medicine-based immunotherapy.

    Nature immunology

    Authors: Evangelos J Giamarellos-Bourboulis, Anna C Aschenbrenner, Michael Bauer, Christoph Bock, Thierry Calandra, Irit Gat-Viks, Evdoxia Kyriazopoulou, Mihaela Lupse, Guillaume Monneret, Peter Pickkers, Joachim L Schultze, Tom van der Poll, Frank L van de Veerdonk, Alexander P J Vlaar, Sebastian Weis, W Joost Wiersinga, Mihai G Netea

  • Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation.

    The Journal of clinical investigation

    Authors: Samuel Young, Christian Schiffer, Alice Wagner, Jannika Patz, Anton Potapenko, Leonie Herrmann, Verena Nordhoff, Tim Pock, Claudia Krallmann, Birgit Stallmeyer, Albrecht Röpke, Michelina Kierzek, Cristina Biagioni, Tao Wang, Lars Haalck, Dirk Deuster, Jan N Hansen, Dagmar Wachten, Benjamin Risse, Hermann M Behre, Stefan Schlatt, Sabine Kliesch, Frank Tüttelmann, Christoph Brenker, Timo Strünker