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Publications

featured publications

  • Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation.

    Science advances

    Authors: Inga V Hochheiser, Heide Behrmann, Gregor Hagelueken, Juan F Rodríguez-Alcázar, Anja Kopp, Eicke Latz, Elmar Behrmann, Matthias Geyer

  • Deficiency in coatomer complex I causes aberrant activation of STING signalling.

    Nature communications

    Authors: Annemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, Chien-Hsiung Yu, Pawat Laohamonthonkul, Cassandra R Harapas, Ronnie Ren Jie Low, Dominic De Nardo, Laura F Dagley, Michael J Mlodzianoski, Kelly L Rogers, Thomas Zillinger, Gunther Hartmann, Michael P Gantier, Marco Gattorno, Matthias Geyer, Stefano Volpi, Sophia Davidson, Seth L Masters

  • Functional Characterization of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G).

    International journal of molecular sciences

    Authors: Roua Hassoun, Constanze Erdmann, Sebastian Schmitt, Setsuko Fujita-Becker, Andreas Mügge, Rasmus R Schröder, Matthias Geyer, Mina Borbor, Kornelia Jaquet, Nazha Hamdani, Hans Georg Mannherz

  • Transcriptional CDK Inhibitors as Potential Treatment Option for Testicular Germ Cell Tumors.

    Cancers

    Authors: Kai Funke, Robert Düster, Prince De-Graft Wilson, Lena Arévalo, Matthias Geyer, Hubert Schorle

  • Functional characterization of the human Cdk10/Cyclin Q complex.

    Open biology

    Authors: Robert Düster, Yanlong Ji, Kuan-Ting Pan, Henning Urlaub, Matthias Geyer

  • Structure-Stability Relationship of NLRP3 Inflammasome-Inhibiting Sulfonylureas.

    ACS omega

    Authors: Tim Keuler, Dominic Ferber, Michael Marleaux, Matthias Geyer, Michael Gütschow

  • Top publication

    Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.

    Nature

    Authors: Inga V Hochheiser, Michael Pilsl, Gregor Hagelueken, Jonas Moecking, Michael Marleaux, Rebecca Brinkschulte, Eicke Latz, Christoph Engel, Matthias Geyer

  • A Surface Plasmon Resonance-Based Strategy to Characterize Interactions of NLR Proteins with Associated Factors.

    Methods in molecular biology (Clifton, N.J.)

    Authors: Jonas Moecking, Matthias Geyer

  • An Assay for the Seeding of Homotypic Pyrin Domain Filament Transitions.

    Methods in molecular biology (Clifton, N.J.)

    Authors: Inga V Hochheiser, Matthias Geyer

  • Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus.

    Journal of clinical immunology

    Authors: Annemarie Steiner, Thomas Reygaerts, Alessandra Pontillo, Isabella Ceccherini, Jonas Moecking, Fiona Moghaddas, Sophia Davidson, Francesco Caroli, Alice Grossi, Fabio Fernandes Morato Castro, Jorge Kalil, Florian N Gohr, Florian I Schmidt, Eva Bartok, Thomas Zillinger, Gunther Hartmann, Matthias Geyer, Marco Gattorno, Leonardo Oliveira Mendonça, Seth L Masters