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Publications

featured publications

  • Protein kinase G1 regulates bone regeneration and rescues diabetic fracture healing.

    JCI insight

    Authors: Nadine Schall, Julian J Garcia, Hema Kalyanaraman, Shyamsundar Pal China, Jenna J Lee, Robert L Sah, Alexander Pfeifer, Renate B Pilz

  • Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β and β-adrenoceptor signalling.

    Molecular metabolism

    Authors: Sukanya Arcot Kannabiran, Dominic Gosejacob, Birte Niemann, Viacheslav O Nikolaev, Alexander Pfeifer

  • Cell-permeable high-affinity tracers for G proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

    British journal of pharmacology

    Authors: Markus Kuschak, Vigneshwaran Namasivayam, Muhammad Rafehi, Jan H Voss, Jaspal Garg, Jonathan G Schlegel, Aliaa Abdelrahman, Stefan Kehraus, Raphael Reher, Jim Küppers, Katharina Sylvester, Sonja Hinz, Michaela Matthey, Daniela Wenzel, Bernd K Fleischmann, Alexander Pfeifer, Asuka Inoue, Michael Gütschow, Gabriele M König, Christa E Müller

  • RGS2: A multifunctional signaling hub that balances brown adipose tissue function and differentiation.

    Molecular metabolism

    Authors: Katarina Klepac, JuHee Yang, Staffan Hildebrand, Alexander Pfeifer

  • The Phosphatase SHP-2 Activates HIF-1α in Wounds In Vivo by Inhibition of 26S Proteasome Activity.

    International journal of molecular sciences

    Authors: Yvonn Heun, Katharina Grundler Groterhorst, Kristin Pogoda, Bjoern F Kraemer, Alexander Pfeifer, Ulrich Pohl, Hanna Mannell

  • A R-induced transcriptional deregulation in astrocytes: An in vitro study.

    Glia

    Authors: Isabel Paiva, Kévin Carvalho, Patrícia Santos, Lucrezia Cellai, Maria Angeliki S Pavlou, Gaurav Jain, Thorsten Gnad, Alexander Pfeifer, Didier Vieau, André Fischer, Luc Buée, Tiago F Outeiro, David Blum

  • cGMP manipulation in cardiometabolic disease: chances and challenges.

    Current opinion in cardiology

    Authors: Jens Jordan, Staffan Hildebrand, Alexander Pfeifer

  • Local anti-angiogenic therapy by magnet-assisted downregulation of SHP2 phosphatase.

    Journal of controlled release : official journal of the Controlled Release Society

    Authors: Sarah Rieck, Yvonn Heun, Alexandra Heidsieck, Olga Mykhaylyk, Alexander Pfeifer, Bernhard Gleich, Hanna Mannell, Daniela Wenzel

  • Top publication

    Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.

    Immunity

    Authors: Lisa Schmidleithner, Yasser Thabet, Eva Schönfeld, Maren Köhne, Daniel Sommer, Zeinab Abdullah, Timothy Sadlon, Collins Osei-Sarpong, Kotha Subbaramaiah, Francesca Copperi, Kristian Haendler, Tamas Varga, Oliver Schanz, Svenja Bourry, Kevin Bassler, Wolfgang Krebs, Annika E Peters, Ann-Kathrin Baumgart, Maria Schneeweiss, Kathrin Klee, Susanne V Schmidt, Simone Nüssing, Jil Sander, Naganari Ohkura, Andreas Waha, Tim Sparwasser, F Thomas Wunderlich, Irmgard Förster, Thomas Ulas, Heike Weighardt, Shimon Sakaguchi, Alexander Pfeifer, Matthias Blüher, Andrew J Dannenberg, Nerea Ferreirós, Louis J Muglia, Claudia Wickenhauser, Simon C Barry, Joachim L Schultze, Marc Beyer

  • Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis.

    EBioMedicine

    Authors: Yvonn Heun, Joachim Pircher, Thomas Czermak, Philipp Bluem, Georg Hupel, Monica Bohmer, Bjoern F Kraemer, Kristin Pogoda, Alexander Pfeifer, Markus Woernle, Andrea Ribeiro, Max Hübner, Simone Kreth, Ralf A Claus, Sebastian Weis, Luisa Ungelenk, Florian Krötz, Ulrich Pohl, Hanna Mannell