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Publications

featured publications

  • Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium.

    eLife

    Authors: Jan N Hansen, Fabian Kaiser, Christina Klausen, Birthe Stüven, Raymond Chong, Wolfgang Bönigk, David U Mick, Andreas Möglich, Nathalie Jurisch-Yaksi, Florian I Schmidt, Dagmar Wachten

  • Sphingolipids controlling ciliary and microvillar function.

    FEBS letters

    Authors: Fabian Kaiser, Mylene Huebecker, Dagmar Wachten

  • Rotational motion and rheotaxis of human sperm do not require functional CatSper channels and transmembrane Ca signaling.

    The EMBO journal

    Authors: Christian Schiffer, Steffen Rieger, Christoph Brenker, Samuel Young, Hussein Hamzeh, Dagmar Wachten, Frank Tüttelmann, Albrecht Röpke, U Benjamin Kaupp, Tao Wang, Alice Wagner, Claudia Krallmann, Sabine Kliesch, Carsten Fallnich, Timo Strünker

  • Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors.

    Biochemical Society transactions

    Authors: Christina Klausen, Fabian Kaiser, Birthe Stüven, Jan N Hansen, Dagmar Wachten

  • Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models.

    Developmental cell

    Authors: Jiami Guo, James M Otis, Sarah K Suciu, Christy Catalano, Lei Xing, Sandii Constable, Dagmar Wachten, Stephanie Gupton, Janice Lee, Amelia Lee, Katherine H Blackley, Travis Ptacek, Jeremy M Simon, Stephane Schurmans, Garret D Stuber, Tamara Caspary, E S Anton

  • Revisiting and Redesigning Light-Activated Cyclic-Mononucleotide Phosphodiesterases.

    Journal of molecular biology

    Authors: Robert Stabel, Birthe Stüven, Jan Niklas Hansen, Heinz G Körschen, Dagmar Wachten, Andreas Möglich

  • Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains.

    Cells

    Authors: Diana N Raju, Jan N Hansen, Sebastian Rassmann, Birthe Stüven, Jan F Jikeli, Timo Strünker, Heinz G Körschen, Andreas Möglich, Dagmar Wachten

  • Sensory primary cilium is a responsive cAMP microdomain in renal epithelia.

    Scientific reports

    Authors: Rinzhin T Sherpa, Ashraf M Mohieldin, Rajasekharreddy Pala, Dagmar Wachten, Rennolds S Ostrom, Surya M Nauli

  • Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations.

    The Journal of biological chemistry

    Authors: Marina A Woeste, Sina Stern, Diana N Raju, Elena Grahn, Dominik Dittmann, Katharina Gutbrod, Peter Dörmann, Jan N Hansen, Sophie Schonauer, Carina E Marx, Hussein Hamzeh, Heinz G Körschen, Johannes M F G Aerts, Wolfgang Bönigk, Heike Endepols, Roger Sandhoff, Matthias Geyer, Thomas K Berger, Frank Bradke, Dagmar Wachten

  • Ciliary Beating Compartmentalizes Cerebrospinal Fluid Flow in the Brain and Regulates Ventricular Development.

    Current biology : CB

    Authors: Emilie W Olstad, Christa Ringers, Jan N Hansen, Adinda Wens, Cecilia Brandt, Dagmar Wachten, Emre Yaksi, Nathalie Jurisch-Yaksi