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Publications

featured publications

  • Eosinophils and Neutrophils Eliminate Migrating Larvae at the Site of Infection in the Context of Extracellular DNA Trap Formation.

    Frontiers in immunology

    Authors: Alexandra Ehrens, Nikolas Rüdiger, Lennart Heepmann, Lara Linnemann, Wiebke Hartmann, Marc P Hübner, Minka Breloer

  • Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside.

    International journal for parasitology. Drugs and drug resistance

    Authors: Marc P Hübner, Simon Townson, Suzanne Gokool, Senyo Tagboto, Mary J Maclean, Guilherme G Verocai, Adrian J Wolstenholme, Stefan J Frohberger, Achim Hoerauf, Sabine Specht, Ivan Scandale, Achim Harder, Martin Glenschek-Sieberth, Steffen R Hahnel, Daniel Kulke

  • Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

    PLoS pathogens

    Authors: Jürgen Krücken, Lindy Holden-Dye, Jennifer Keiser, Roger K Prichard, Simon Townson, Benjamin L Makepeace, Marc P Hübner, Steffen R Hahnel, Ivan Scandale, Achim Harder, Daniel Kulke

  • Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening.

    PLoS neglected tropical diseases

    Authors: Narcisse V T Gandjui, Abdel J Njouendou, Eric N Gemeg, Fanny F Fombad, Manuel Ritter, Chi A Kien, Valerine C Chunda, Jerome Fru, Mathias E Esum, Marc P Hübner, Peter A Enyong, Achim Hoerauf, Samuel Wanji

  • Human filariasis-contributions of the Litomosoides sigmodontis and Acanthocheilonema viteae animal model.

    Parasitology research

    Authors: Frederic Risch, Manuel Ritter, Achim Hoerauf, Marc P Hübner

  • Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections.

    PLoS neglected tropical diseases

    Authors: Andrea Schiefer, Marc P Hübner, Anna Krome, Christine Lämmer, Alexandra Ehrens, Tilman Aden, Marianne Koschel, Helene Neufeld, Lillibeth Chaverra-Muñoz, Rolf Jansen, Stefan Kehraus, Gabriele M König, Domen Pogorevc, Rolf Müller, Marc Stadler, Stephan Hüttel, Thomas Hesterkamp, Karl Wagner, Kenneth Pfarr, Achim Hoerauf

  • Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A.

    Pharmaceutics

    Authors: Anna K Krome, Tim Becker, Stefan Kehraus, Andrea Schiefer, Christian Steinebach, Tilman Aden, Stefan J Frohberger, Álvaro López Mármol, Dnyaneshwar Kapote, Rolf Jansen, Lillibeth Chaverra-Muñoz, Marc P Hübner, Kenneth Pfarr, Thomas Hesterkamp, Marc Stadler, Michael Gütschow, Gabriele M König, Achim Hoerauf, Karl G Wagner

  • Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.

    PLoS neglected tropical diseases

    Authors: Marc P Hübner, Coralie Martin, Sabine Specht, Marianne Koschel, Bettina Dubben, Stefan J Frohberger, Alexandra Ehrens, Martina Fendler, Dominique Struever, Edward Mitre, Nathaly Vallarino-Lhermitte, Suzanne Gokool, Sara Lustigman, Manfred Schneider, Simon Townson, Achim Hoerauf, Ivan Scandale

  • Macrophages Mediate Increased CD8 T Cell Inflammation During Weight Loss in Formerly Obese Mice.

    Frontiers in endocrinology

    Authors: Jayagopi Surendar, Indulekha Karunakaran, Stefan J Frohberger, Marianne Koschel, Achim Hoerauf, Marc P Hübner

  • Top publication

    Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2.

    Immunity

    Authors: Thomas Ostendorf, Thomas Zillinger, Katarzyna Andryka, Thais Marina Schlee-Guimaraes, Saskia Schmitz, Samira Marx, Kübra Bayrak, Rebecca Linke, Sarah Salgert, Julia Wegner, Tatjana Grasser, Sonja Bauersachs, Leon Soltesz, Marc P Hübner, Maximilian Nastaly, Christoph Coch, Matthias Kettwig, Ingo Roehl, Marco Henneke, Achim Hoerauf, Winfried Barchet, Jutta Gärtner, Martin Schlee, Gunther Hartmann, Eva Bartok