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featured publications

  • Activating p53 with a Mutant-Specific Small Molecule.

    bioRxiv : the preprint server for biology

    Authors: Xijun Zhu, Woong Sub Byun, Dominika Ewa Pieńkowska, Kha The Nguyen, Jan Gerhartz, Qixiang Geng, Tian Qiu, Jianing Zhong, Zixuan Jiang, Mengxiong Wang, Roman C Sarott, Stephen M Hinshaw, Tinghu Zhang, Laura D Attardi, Radosław P Nowak, Nathanael S Gray

  • Microaxial Flow Pump Use and Renal Outcomes in Infarct-Related Cardiogenic Shock - a Secondary Analysis of the DanGer Shock Trial.

    Circulation

    Authors: Elric Zweck, Christian Hassager, Rasmus P Beske, Lisette O Jensen, Hans Eiskjær, Norman Mangner, Amin Polzin, P Christian Schulze, Carsten Skurk, Peter Nordbeck, Peter Clemmensen, Vasileios Panoulas, Sebastian Zimmer, Andreas Schäfer, Malte Kelm, Thomas Engstrøm, Lene Holmvang, Anders Junker, Henrik Schmidt, Christian J Terkelsen, Axel Linke, Ralf Westenfeld, Jacob E Møller

  • Microaxial Flow Pump Hemodynamic and Metabolic Effects in Infarct-Related Cardiogenic Shock: A Substudy of the DanGer Shock Randomized Clinical Trial.

    JAMA cardiology

    Authors: Nanna Louise Junker Udesen, Rasmus Paulin Beske, Christian Hassager, Lisette Okkels Jensen, Hans Eiskjær, Norman Mangner, Amin Polzin, P Christian Schulze, Carsten Skurk, Peter Nordbeck, Peter Clemmensen, Vasileios Panoulas, Sebastian Zimmer, Andreas Schäfer, Nikos Werner, Martin Frydland, Lene Holmvang, Jesper Kjærgaard, Thomas Engstøm, Henrik Schmidt, Anders Junker, Christian Juhl Terkelsen, Steffen Christensen, Axel Linke, Jacob Eifer Møller

  • Postoperative Innate Immune Dysregulation, Proteomic, and Monocyte Epigenomic Changes After Colorectal Surgery: A Substudy of a Randomized Controlled Trial.

    Anesthesia and analgesia

    Authors: Kim I Albers-Warlé, Leonie S Helder, Laszlo A Groh, Fatih Polat, Ivo F Panhuizen, Marc M J Snoeck, Matthijs Kox, Lucas van Eijk, Leo A B Joosten, Mihai G Netea, Yutaka Negishi, Musa Mhlanga, Christiaan Keijzer, Gert-Jan Scheffer, Michiel C Warlé

  • Proposing GLMN, encoding glomulin, as a novel gene for Dowling-Degos disease.

    The British journal of dermatology

    Authors: Sheetal Kumar, Regina C Betz, Jorge Frank

  • Cryo-EM structure of the human native plasma coagulation factor XIII complex.

    Blood

    Authors: Sneha Singh, Gregor Hagelueken, Deniz Ugurlar, Samhitha Urs Ramaraje Urs, Amit Sharma, Manoranjan Mahapatra, Friedel Drepper, Diana Imhof, Pitter F Huesgen, Johannes Oldenburg, Matthias Geyer, Arijit Biswas

  • Genetic Prediction Modeling in Large Cohort Studies via Boosting Targeted Loss Functions.

    Statistics in medicine

    Authors: Hannah Klinkhammer, Christian Staerk, Carlo Maj, Peter M Krawitz, Andreas Mayr

  • Benchmarking methods for computing local sensitivities in ordinary differential equation models at dynamic and steady states.

    PloS one

    Authors: Polina Lakrisenko, Dilan Pathirana, Daniel Weindl, Jan Hasenauer

  • Deep Learning to Predict the Future Growth of Geographic Atrophy from Fundus Autofluorescence.

    Ophthalmology science

    Authors: Anish Salvi, Julia Cluceru, Simon S Gao, Christina Rabe, Courtney Schiffman, Qi Yang, Aaron Y Lee, Pearse A Keane, Srinivas R Sadda, Frank G Holz, Daniela Ferrara, Neha Anegondi

  • A Quantitative Comparison Between Human and Artificial Intelligence in the Detection of Focal Cortical Dysplasia.

    Investigative radiology

    Authors: Lennart Walger, Tobias Bauer, David Kügler, Matthias H Schmitz, Fabiane Schuch, Christophe Arendt, Tobias Baumgartner, Johannes Birkenheier, Valeri Borger, Christoph Endler, Franziska Grau, Christian Immanuel, Markus Kölle, Patrick Kupczyk, Asadeh Lakghomi, Sarah Mackert, Elisabeth Neuhaus, Julia Nordsiek, Anna-Maria Odenthal, Karmele Olaciregui Dague, Laura Ostermann, Jan Pukropski, Attila Racz, Klaus von der Ropp, Frederic Carsten Schmeel, Felix Schrader, Aileen Sitter, Alexander Unruh-Pinheiro, Marilia Voigt, Martin Vychopen, Philip von Wedel, Randi von Wrede, Ulrike Attenberger, Hartmut Vatter, Alexandra Philipsen, Albert Becker, Martin Reuter, Elke Hattingen, Josemir W Sander, Alexander Radbruch, Rainer Surges, Theodor Rüber