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  • Blood immune cell profiling in adults with longstanding type 1 diabetes is associated with macrovascular complications.

    Frontiers in immunology

    Authors: Xuehui He, Xinhui Wang, Julia van Heck, Bram van Cranenbroek, Esther van Rijssen, Rinke Stienstra, Mihai G Netea, Irma Joosten, Cees J Tack, Hans J P M Koenen

  • Irinotecan and temozolomide in combination with dasatinib and rapamycin versus irinotecan and temozolomide for patients with relapsed or refractory neuroblastoma (RIST-rNB-2011): a multicentre, open-label, randomised, controlled, phase 2 trial.

    The Lancet. Oncology

    Authors: Selim Corbacioglu, Holger Lode, Susanne Ellinger, Florian Zeman, Meinolf Suttorp, Gabriele Escherich, Konrad Bochennek, Bernd Gruhn, Peter Lang, Marius Rohde, Klaus Michael Debatin, Daniel Steinbach, Andreas Beilken, Ruth Ladenstein, Rainer Spachtholz, Peter Heiss, Dirk Hellwig, Anja Tröger, Michael Koller, Karin Menhart, Markus J Riemenschneider, Saida Zoubaa, Silke Kietz, Marcus Jakob, Gunhild Sommer, Tilman Heise, Patrick Hundsdörfer, Ingrid Kühnle, Dagmar Dilloo, Stefan Schönberger, Georg Schwabe, Irene von Luettichau, Norbert Graf, Paul-Gerhardt Schlegel, Michael Frühwald, Norbert Jorch, Michael Paulussen, Dominik T Schneider, Markus Metzler, Alfred Leipold, Michaela Nathrath, Thomas Imschweiler, Holger Christiansen, Irene Schmid, Roman Crazzolara, Naghmeh Niktoreh, Gunnar Cario, Joerg Faber, Martin Demmert, Florian Babor, Birgit Fröhlich, Stefan Bielack, Toralf Bernig, Johann Greil, Angelika Eggert, Thorsten Simon, Juergen Foell

  • Beneficial Effects of Synbiotics on the Gut Microbiome in Individuals with Low Fiber Intake: Secondary Analysis of a Double-Blind, Randomized Controlled Trial.

    Nutrients

    Authors: Aakash Mantri, Linda Klümpen, Waldemar Seel, Peter Krawitz, Peter Stehle, Bernd Weber, Leonie Koban, Hilke Plassmann, Marie-Christine Simon

  • Stratified analyses refine association between TLR7 rare variants and severe COVID-19.

    HGG advances

    Authors: Jannik Boos, Caspar I van der Made, Gayatri Ramakrishnan, Eamon Coughlan, Rosanna Asselta, Britt-Sabina Löscher, Luca V C Valenti, Rafael de Cid, Luis Bujanda, Antonio Julià, Erola Pairo-Castineira, J Kenneth Baillie, Sandra May, Berina Zametica, Julia Heggemann, Agustín Albillos, Jesus M Banales, Jordi Barretina, Natalia Blay, Paolo Bonfanti, Maria Buti, Javier Fernandez, Sara Marsal, Daniele Prati, Luisa Ronzoni, Nicoletta Sacchi, Joachim L Schultze, Olaf Riess, Andre Franke, Konrad Rawlik, David Ellinghaus, Alexander Hoischen, Axel Schmidt, Kerstin U Ludwig

  • Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Jonathan Vogelgsang, Niels Hansen, Melina Stark, Michael Wagner, Hans Klafki, Barbara Marcos Morgado, Anke Jahn-Brodmann, Björn Schott, Hermann Esselmann, Chris Bauer, Johannes Schuchhardt, Luca Kleineidam, Steffen Wolfsgruber, Oliver Peters, Luisa-Sophie Schneider, Xiao Wang, Felix Menne, Josef Priller, Eike Spruth, Slawek Altenstein, Andrea Lohse, Anja Schneider, Klaus Fliessbach, Ina Vogt, Claudia Bartels, Frank Jessen, Ayda Rostamzadeh, Emrah Duezel, Wenzel Glanz, Enise Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris Rauchmann, Selim Guersel, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias Munk, Carolin Sanzenbacher, Annika Spottke, Nina Roy-Kluth, Michael Heneka, Frederic Brosseron, Alfredo Ramierez, Matthias Schmid, Jens Wiltfang

  • Efficient parameter estimation for ODE models of cellular processes using semi-quantitative data.

    Bioinformatics (Oxford, England)

    Authors: Domagoj Dorešić, Stephan Grein, Jan Hasenauer

  • Approximating facial expression effects on diagnostic accuracy via generative AI in medical genetics.

    Bioinformatics (Oxford, England)

    Authors: Tanviben Patel, Amna A Othman, Ömer Sümer, Fabio Hellman, Peter Krawitz, Elisabeth André, Molly E Ripper, Chris Fortney, Susan Persky, Ping Hu, Cedrik Tekendo-Ngongang, Suzanna Ledgister Hanchard, Kendall A Flaharty, Rebekah L Waikel, Dat Duong, Benjamin D Solomon

  • T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis.

    Nature neuroscience

    Authors: Shreeya Kedia, Hao Ji, Ruoqing Feng, Peter Androvic, Lena Spieth, Lu Liu, Jonas Franz, Hanna Zdiarstek, Katrin Perez Anderson, Cem Kaboglu, Qian Liu, Nicola Mattugini, Fatma Cherif, Danilo Prtvar, Ludovico Cantuti-Castelvetri, Arthur Liesz, Martina Schifferer, Christine Stadelmann, Sabina Tahirovic, Ozgun Gokce, Mikael Simons

  • Microglia contribute to neuronal synchrony despite endogenous ATP-related phenotypic transformation in acute mouse brain slices.

    Nature communications

    Authors: Péter Berki, Csaba Cserép, Zsuzsanna Környei, Balázs Pósfai, Eszter Szabadits, Andor Domonkos, Anna Kellermayer, Miklós Nyerges, Xiaofei Wei, Istvan Mody, Araki Kunihiko, Heinz Beck, He Kaikai, Wang Ya, Nikolett Lénárt, Zhaofa Wu, Miao Jing, Yulong Li, Attila I Gulyás, Ádám Dénes

  • Study Protocol of a Randomized, Two-Arm, Phase I/II Trial Investigating the Feasibility, Safety, and Efficacy of Local Treatment with US-Guided High-Intensity Focused Ultrasound in Combination with Palliative Chemotherapy in Inoperable Pancreatic Cancer.

    Journal of clinical medicine

    Authors: Milka Marinova, David-Alexis Khouri, Jim Küppers, Olga Ramig, Holger M Strunk, Johannes Breuers, Julia Fazaal, Christine Fuhrmann, Martin Coenen, Christian Möhring, Taotao Zhou, Xin Zhou, Thomas Anhalt, Farsaneh Sadeghlar, Marcus Thudium, Rupert Conrad, Georg Feldmann, Peter Brossart, Tim R Glowka, Jörg C Kalff, Markus Essler, Christian P Strassburg, Yon-Dschun Ko, Ingo G H Schmidt-Wolf, Maria Gonzalez-Carmona