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  • The efficacy of the benzimidazoles oxfendazole and flubendazole against is dependent on the adaptive and innate immune system.

    Frontiers in microbiology

    Authors: Frederic Risch, Johanna F Scheunemann, Julia J Reichwald, Benjamin Lenz, Alexandra Ehrens, Joséphine Gal, Frédéric Fercoq, Marianne Koschel, Martina Fendler, Achim Hoerauf, Coralie Martin, Marc P Hübner

  • Stage-Dependent Increase of Systemic Immune Activation and CCR5CD4 T Cells in Filarial Driven Lymphedema in Ghana and Tanzania.

    Pathogens (Basel, Switzerland)

    Authors: Abu Abudu Rahamani, Sacha Horn, Manuel Ritter, Anja Feichtner, Jubin Osei-Mensah, Vera Serwaa Opoku, Linda Batsa Debrah, Thomas F Marandu, Antelmo Haule, Jacklina Mhidze, Abdallah Ngenya, Max Demetrius, Ute Klarmann-Schulz, Michael Hoelscher, Christof Geldmacher, Achim Hoerauf, Akili Kalinga, Alexander Y Debrah, Inge Kroidl

  • The design and development of a study protocol to investigate Onchocerca volvulus, Loa loa and Mansonella perstans-mediated modulation of the metabolic and immunological profile in lean and obese individuals in Cameroon.

    PloS one

    Authors: Benjamin Lenz, Beng Amuam Andrew, Manuel Ritter, Indulekha Karunakaran, Narcisse Victor Tchamatchoua Gandjui, Lucy Cho Nchang, Jayagopi Surendar, Anita Obi Bate Ebob, Alexandra Ehrens, Ute Klarmann-Schulz, Arcangelo Ricchiuto, Janina M Kuehlwein, Fanny Fri Fombad, Ambe Marius Ngwa, Tatiana Djikeussi Katcho, Achim Hoerauf, Samuel Wanji, Marc P Hübner

  • A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis.

    PLoS neglected tropical diseases

    Authors: Nicholas O Opoku, Felix Doe, Bettina Dubben, Nicole Fetcho, Kerstin Fischer, Peter U Fischer, Shelter Gordor, Charles W Goss, Michael E Gyasi, Achim Hoerauf, Augustine R Hong, Eric Kanza, Christopher L King, Ruth Laryea, Daphne Lew, Mahmood A Seidu, Gary J Weil

  • Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode .

    Vaccines

    Authors: Johanna F Scheunemann, Frederic Risch, Julia J Reichwald, Benjamin Lenz, Anna-Lena Neumann, Stephan Garbe, Stefan J Frohberger, Marianne Koschel, Jesuthas Ajendra, Maximilian Rothe, Eicke Latz, Christoph Coch, Gunther Hartmann, Beatrix Schumak, Achim Hoerauf, Marc P Hübner

  • First genome-wide association study for lymphatic filariasis in a West African population points to a human leukocyte antigen-mediated disease pathophysiology.

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    Authors: Sandeep Grover, Vera S Opoku, Linda B Debrah, Carlo Maj, Jubin Osei-Mensah, Derrick A Mensah, Achim Hoerauf, Alexander Y Debrah, Johannes Schumacher, Kenneth Pfarr

  • Reduced Type 2 Innate Lymphocyte Cell Frequencies in Patent -Infected Individuals.

    Pathogens (Basel, Switzerland)

    Authors: Ruth S E Tamadaho, Jubin Osei-Mensah, Kathrin Arndts, Linda Batsa Debrah, Alexander Y Debrah, Laura E Layland, Achim Hoerauf, Kenneth Pfarr, Manuel Ritter

  • Unraveling cross-reactivity of anti-glycan IgG responses in filarial nematode infections.

    Frontiers in immunology

    Authors: Laudine M C Petralia, Angela van Diepen, Dieu-Linh Nguyen, Lena A Lokker, Erliyani Sartono, Sasisekhar Bennuru, Thomas B Nutman, Kenneth Pfarr, Achim Hoerauf, Samuel Wanji, Jeremy M Foster, Cornelis H Hokke

  • Filariasis research - from basic research to drug development and novel diagnostics, over a decade of research at the Institute for Medical Microbiology, Immunology and Parasitology, Bonn, Germany.

    Frontiers in tropical diseases

    Authors: Indulekha Karunakaran, Manuel Ritter, Kenneth Pfarr, Ute Klarmann-Schulz, Alexander Yaw Debrah, Linda Batsa Debrah, Gnatoulma Katawa, Samuel Wanji, Sabine Specht, Tomabu Adjobimey, Marc P Hübner, Achim Hoerauf

  • The pipeline for drugs for control and elimination of neglected tropical diseases: 1. Anti-infective drugs for regulatory registration.

    Parasites & vectors

    Authors: Kenneth M Pfarr, Anna K Krome, Issraa Al-Obaidi, Hannah Batchelor, Michel Vaillant, Achim Hoerauf, Nicholas O Opoku, Annette C Kuesel