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  • Baricitinib provides rapid and sustained improvements in absolute EASI and SCORAD outcomes in adults with moderate-to-severe atopic dermatitis.

    The Journal of dermatological treatment

    Authors: Jacob P Thyssen, Thomas Bieber, C Elise Kleyn, Audrey Nosbaum, Susanne Grond, Helmut Petto, Elisabeth Riedl, Andreas Wollenberg

  • Conditional NKT Cell Depletion in Mice Reveals a Negative Feedback Loop That Regulates CTL Cross-Priming.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Christoph Heuser-Loy, Ann-Kathrin Baumgart, Carl-Philipp Hackstein, Christina J F Courrèges, Marie-Sophie Philipp, Christoph A Thaiss, Tristan Holland, César Evaristo, Natalio Garbi, Christian Kurts

  • Early combination therapy of COVID-19 in high-risk patients.

    Infection

    Authors: Hans Martin Orth, Charlotte Flasshove, Moritz Berger, Sandra Tessa Hattenhauer, Kaja D Biederbick, Rebekka Mispelbaum, Uwe Klein, Jannik Stemler, Matthis Fisahn, Anna D Doleschall, Ben-Niklas Baermann, Eva Koenigshausen, Olga Tselikmann, Alexander Killer, Clara de Angelis, Smaranda Gliga, Johannes Stegbauer, Nikolai Spuck, Gerda Silling, Jürgen K Rockstroh, Christian P Strassburg, Peter Brossart, Jens P Panse, Björn-Erik Ole Jensen, Tom Luedde, Christoph Boesecke, Annkristin Heine, Oliver A Cornely, Malte B Monin

  • BCG vaccination impacts the epigenetic landscape of progenitor cells in human bone marrow.

    bioRxiv : the preprint server for biology

    Authors: Sarah J Sun, Raúl Aguirre-Gamboa, L Charlotte J de Bree, Joaquin Sanz, Anne Dumaine, Leo A B Joosten, Maziar Divangahi, Mihai G Netea, Luis B Barreiro

  • Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human.

    eLife

    Authors: Simon Schneider, Andjela Kovacevic, Michelle Mayer, Ann-Kristin Dicke, Lena Arévalo, Sophie A Koser, Jan N Hansen, Samuel Young, Christoph Brenker, Sabine Kliesch, Dagmar Wachten, Gregor Kirfel, Timo Struenker, Frank Tüttelmann, Hubert Schorle

  • Refining accuracy of RV-PA coupling in patients undergoing transcatheter tricuspid valve treatment.

    Clinical research in cardiology : official journal of the German Cardiac Society

    Authors: Atsushi Sugiura, Tetsu Tanaka, Refik Kavsur, Can Öztürk, Miriam Silaschi, Tadahiro Goto, Marcel Weber, Sebastian Zimmer, Georg Nickenig, Johanna Vogelhuber

  • Genetic and non-genetic drivers of platelet reactivity in healthy Tanzanian individuals.

    Journal of thrombosis and haemostasis : JTH

    Authors: Vesla I Kullaya, Godfrey S Temba, Nadira Vadaq, Judith Njau, Collins K Boahen, Bongani B Nkambule, Florian Thibord, Ming-Huei Chen, Tal Pecht, Furaha Lyamuya, Vinod Kumar, Mihai G Netea, Blandina T Mmbaga, Andre van der Ven, Andrew D Johnson, Quirijn de Mast

  • The reversible inhibitor SR-4835 binds Cdk12/Cyclin K in a non-canonical G-loop conformation.

    The Journal of biological chemistry

    Authors: Maximilian Schmitz, Ines H Kaltheuner, Kanchan Anand, Robert Düster, Jonas Moecking, Andrii Monastyrskyi, Derek R Duckett, William R Roush, Matthias Geyer

  • Cooperative activation of human TLR9 and consequences for the clinical development of antisense and CpG oligodeoxynucleotides.

    Molecular therapy. Nucleic acids

    Authors: Gunther Hartmann

  • Trans-ancestry polygenic models for the prediction of LDL blood levels: an analysis of the United Kingdom Biobank and Taiwan Biobank.

    Frontiers in genetics

    Authors: Emadeldin Hassanin, Ko-Han Lee, Tzung-Chien Hsieh, Rana Aldisi, Yi-Lun Lee, Dheeraj Bobbili, Peter Krawitz, Patrick May, Chien-Yu Chen, Carlo Maj