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  • The reversible inhibitor SR-4835 binds Cdk12/Cyclin K in a non-canonical G-loop conformation.

    The Journal of biological chemistry

    Authors: Maximilian Schmitz, Ines H Kaltheuner, Kanchan Anand, Robert Düster, Jonas Moecking, Andrii Monastyrskyi, Derek R Duckett, William R Roush, Matthias Geyer

  • Cooperative activation of human TLR9 and consequences for the clinical development of antisense and CpG oligodeoxynucleotides.

    Molecular therapy. Nucleic acids

    Authors: Gunther Hartmann

  • pyPESTO: A modular and scalable tool for parameter estimation for dynamic models.

    Bioinformatics (Oxford, England)

    Authors: Yannik Schälte, Fabian Fröhlich, Paul J Jost, Jakob Vanhoefer, Dilan Pathirana, Paul Stapor, Polina Lakrisenko, Dantong Wang, Elba Raimúndez, Simon Merkt, Leonard Schmiester, Philipp Städter, Stephan Grein, Erika Dudkin, Domagoj Doresic, Daniel Weindl, Jan Hasenauer

  • [Results of Endoscopic Screening and Therapy of the Duodenum in MUTYH-associated Polyposis].

    Zentralblatt fur Chirurgie

    Authors: Sonja Haas, Christian P Strassburg, Jacob Nattermann, Robert Hueneburg

  • Trans-ancestry polygenic models for the prediction of LDL blood levels: an analysis of the United Kingdom Biobank and Taiwan Biobank.

    Frontiers in genetics

    Authors: Emadeldin Hassanin, Ko-Han Lee, Tzung-Chien Hsieh, Rana Aldisi, Yi-Lun Lee, Dheeraj Bobbili, Peter Krawitz, Patrick May, Chien-Yu Chen, Carlo Maj

  • Host-pathogen interactions from a metabolic perspective: methods of investigation.

    Microbes and infection

    Authors: Caroline Demangel, Laura Surace

  • Environmental bisphenol A exposure triggers trained immunity-related pathways in monocytes.

    Frontiers in immunology

    Authors: Marcello Dallio, Lorenzo Ventriglia, Mario Romeo, Flavia Scognamiglio, Nadia Diano, Martina Moggio, Marina Cipullo, Annachiara Coppola, Athanasios Ziogas, Mihai G Netea, Alessandro Federico

  • On-treatment Modified Glasgow Prognostic Score Provides Predictive Information Complementary to Radiological Staging in Metastatic Urothelial Carcinoma on Immunotherapy.

    European urology oncology

    Authors: Jonas Saal, Viktor Grünwald, Tobias Bald, Manuel Ritter, Peter Brossart, Yoshihiko Tomita, Arndt Hartmann, Michael Hölzel, Markus Eckstein, Niklas Klümper

  • Acid ceramidase regulates innate immune memory.

    Cell reports

    Authors: Nils Rother, Cansu Yanginlar, Geoffrey Prévot, Inge Jonkman, Maaike Jacobs, Mandy M T van Leent, Julia van Heck, Vasiliki Matzaraki, Anthony Azzun, Judit Morla-Folch, Anna Ranzenigo, William Wang, Roy van der Meel, Zahi A Fayad, Niels P Riksen, Luuk B Hilbrands, Rik G H Lindeboom, Joost H A Martens, Michiel Vermeulen, Leo A B Joosten, Mihai G Netea, Willem J M Mulder, Johan van der Vlag, Abraham J P Teunissen, Raphaël Duivenvoorden

  • Pediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunction.

    British journal of pharmacology

    Authors: David F Colón, Carlos W Wanderley, Walter M Turato, Vanessa F Borges, Marcelo Franchin, Fernanda V S Castanheira, Daniele Nascimento, Douglas Prado, Mikhael Haruo Fernandes de Lima, Leila C Volpon, Silvia K Kavaguti, Ana P Carlotti, Fabio Carmona, Bernardo S Franklin, Thiago M Cunha, Jose C Alves-Filho, Fernando Q Cunha