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  • Prospective selective embedding of radical prostatectomy specimens is not inferior to full embedding regarding established and new prognostic parameters.

    Virchows Archiv : an international journal of pathology

    Authors: Marit Bernhardt, Oliver Hommerding, Tobias Kreft, Leonie Weinhold, Matthias Schmid, Glen Kristiansen

  • TCA metabolism regulates DNA hypermethylation in LPS and -induced immune tolerance.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Abhimanyu, Santiago Carrero Longlax, Tomoki Nishiguchi, Malik Ladki, Daanish Sheikh, Amera L Martinez, Emily M Mace, Sandra L Grimm, Thaleia Caldwell, Alexandra Portillo Varela, Rajagopal V Sekhar, Anna M Mandalakas, Mandla Mlotshwa, Sibuse Ginidza, Jeffrey D Cirillo, Robert S Wallis, Mihai G Netea, Reinout van Crevel, Cristian Coarfa, Andrew R DiNardo

  • Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B.

    Journal of medicinal chemistry

    Authors: Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland Smith, L Emilia Basantes, Katharina Schwandt, Aaron Babendreyer, Timothy Chavez, Nicholas McKee, Vijay Gokhale, Sebastian Kallabis, Felix Meissner, Samantha N Rokey, Travis Dunckley, William R Montfort, Walter Becker, Christopher Hulme

  • Interleukin 38 reduces antigen-presentation capacity and antibody production after vaccination.

    Vaccine

    Authors: Lisa U Teufel, Esther J M Taks, Jelle van Gemert, Mihaela Neacsu, Konstantin Föhse, Joshua Gillard, Dimitri A Diavatopoulos, Marien I de Jonge, Mihai G Netea, Leo A B Joosten, Rob J W Arts

  • Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis.

    The Journal of infection

    Authors: Muhammed D Aksu, Tijmen van der Ent, Zhenhua Zhang, Anca L Riza, Aline H de Nooijer, Isis Ricaño-Ponce, Nico Janssen, Job J Engel, Ioana Streata, Helga Dijkstra, Heidi Lemmers, Inge Grondman, Valerie A C M Koeken, Eleni Antoniadou, Nikolaos Antonakos, Frank L van de Veerdonk, Yang Li, Evangelos J Giamarellos-Bourboulis, Mihai G Netea, Athanasios Ziogas

  • Deep Learning Virtual Contrast-Enhanced T1 Mapping for Contrast-Free Myocardial Extracellular Volume Assessment.

    Journal of the American Heart Association

    Authors: Sebastian Nowak, Leon M Bischoff, Lenhard Pennig, Kenan Kaya, Alexander Isaak, Maike Theis, Wolfgang Block, Claus C Pieper, Daniel Kuetting, Sebastian Zimmer, Georg Nickenig, Ulrike I Attenberger, Alois M Sprinkart, Julian A Luetkens

  • T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels.

    Immunity

    Authors: Julia M Messmer, Calvin Thommek, Manuel Piechutta, Varun Venkataramani, Rebekka Wehner, Dana Westphal, Marc Schubert, Chanté D Mayer, Maike Effern, Anna S Berghoff, Daniel Hinze, Iris Helfrich, Dirk Schadendorf, Wolfgang Wick, Michael Hölzel, Matthia A Karreman, Frank Winkler

  • Transient MRI changes and neurological deterioration in glioblastoma upon SARS-CoV-2 infection.

    Journal of cancer research and clinical oncology

    Authors: Thomas Zeyen, Lea L Friker, Daniel Paech, Niklas Schaefer, Johannes Weller, Valentina Zschernack, Julian P Layer, Matthias Schneider, Anna-Laura Potthoff, Marit Bernhardt, Christine Sanders, Glen Kristiansen, Michael Hoelzel, Eleni Gkika, Alexander Radbruch, Torsten Pietsch, Ulrich Herrlinger, Christina Schaub

  • Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4 T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.

    Gastroenterology

    Authors: Veronika Horn, Camila A Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Lissner, Thomas Conrad, Mir-Farzin Mashreghi, Sebastian Zundler, Elena Sonnenberg, Michael Schumann, Lea-Maxie Haag, Dieter Beule, Lukas Flatz, Zlatko Trjanoski, Geert D'Haens, Carl Weidinger, Henrik E Mei, Britta Siegmund, Kevin Thurley, Ahmed N Hegazy

  • The impact of lenvatinib on sarcopenia in patients with advanced unresectable hepatocellular carcinoma.

    Scientific reports

    Authors: Michael Praktiknjo, Ana S Pena Solano, Farsaneh Sadeghlar, Thomas Welchowski, Matthias Schmid, Christian Möhring, Taotao Zhou, Robert Mahn, Malte B Monin, Carsten Meyer, Georg Feldmann, Peter Brossart, Cornelius van Beekum, Alexander Semaan, Hanno Matthaei, Steffen Manekeller, Alois M Sprinkart, Sebastian Nowak, Julian Luetkens, Jörg C Kalff, Christian P Strassburg, Maria A González-Carmona