Publications

Early improvements in signs and symptoms predict clinical response to baricitinib in patients with moderate-to-severe atopic dermatitis.

21/07/2023 Clinical and experimental dermatology

Authors: Thomas Bieber, Jacob P Thyssen, Alan D Irvine, Yuichiro Tsunemi, Yun-Fei Chen, Luna Sun, Andrea Schloebe, Elisabeth Riedl, Michael J Cork

Corrigendum to "Dissecting the genetic heterogeneity of gastric cancer".

20/07/2023 EBioMedicine

Authors: Timo Hess, Carlo Maj, Jan Gehlen, Oleg Borisov, Stephan L Haas, Ines Gockel, Michael Vieth, Guillaume Piessen, Hakan Alakus, Yogesh Vashist, Carina Pereira, Michael Knapp, Vitalia Schüller, Alexander Quaas, Heike I Grabsch, Jessica Trautmann, Ewa Malecka-Wojciesko, Anna Mokrowiecka, Jan Speller, Andreas Mayr, Julia Schröder, Axel M Hillmer, Dominik Heider, Florian Lordick, Ángeles Pérez-Aísa, Rafael Campo, Jesús Espinel, Fernando Geijo, Concha Thomson, Luis Bujanda, Federico Sopeña, Ángel Lanas, María Pellisé, Claudia Pauligk, Thorsten Oliver Goetze, Carolin Zelck, Julian Reingruber, Emadeldin Hassanin, Peter Elbe, Sandra Alsabeah, Mats Lindblad, Magnus Nilsson, Nicole Kreuser, René Thieme, Francesca Tavano, Roberta Pastorino, Dario Arzani, Roberto Persiani, Jin-On Jung, Henrik Nienhüser, Katja Ott, Ralf R Schumann, Oliver Kumpf, Susen Burock, Volker Arndt, Anna Jakubowska, Małgorzta Ławniczak, Victor Moreno, Vicente Martín, Manolis Kogevinas, Marina Pollán, Justyna Dąbrowska, Antonio Salas, Olivier Cussenot, Anne Boland-Auge, Delphine Daian, Jean-Francois Deleuze, Erika Salvi, Maris Teder-Laving, Gianluca Tomasello, Margherita Ratti, Chiara Senti, Valli De Re, Agostino Steffan, Arnulf H Hölscher, Katharina Messerle, Christiane Josephine Bruns, Armands Sīviņš, Inga Bogdanova, Jurgita Skieceviciene, Justina Arstikyte, Markus Moehler, Hauke Lang, Peter P Grimminger, Martin Kruschewski, Nikolaos Vassos, Claus Schildberg, Philipp Lingohr, Karsten Ridwelski, Hans Lippert, Nadine Fricker, Peter Krawitz, Per Hoffmann, Markus M Nöthen, Lothar Veits, Jakob R Izbicki, Adrianna Mostowska, Federico Martinón-Torres, Daniele Cusi, Rolf Adolfsson, Geraldine Cancel-Tassin, Aksana Höblinger, Ernst Rodermann, Monika Ludwig, Gisela Keller, Andres Metspalu, Hermann Brenner, Joerg Heller, Markus Neef, Michael Schepke, Franz Ludwig Dumoulin, Lutz Hamann, Renato Cannizzaro, Michele Ghidini, Dominik Plaßmann, Michael Geppert, Peter Malfertheiner, Olivier Glehen, Tomasz Skoczylas, Marek Majewski, Jan Lubiński, Orazio Palmieri, Stefania Boccia, Anna Latiano, Nuria Aragones, Thomas Schmidt, Mário Dinis-Ribeiro, Rui Medeiros, Salah-Eddin Al-Batran, Mārcis Leja, Juozas Kupcinskas, María A García-González, Marino Venerito, Johannes Schumacher

Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging.

19/07/2023 Proceedings of the National Academy of Sciences of the United States of America

Authors: Isabel J Bauer, Ping Fang, Katrin F Lämmle, Sofia Tyystjärvi, Dominik Alterauge, Dirk Baumjohann, Hongsup Yoon, Thomas Korn, Hartmut Wekerle, Naoto Kawakami

Dendritic cell type 3 arises from Ly6C monocyte-dendritic cell progenitors.

19/07/2023 Immunity

Authors: Zhaoyuan Liu, Haiting Wang, Ziyi Li, Regine J Dress, Yiwen Zhu, Shuangyan Zhang, Donatella De Feo, Wan Ting Kong, Peiliang Cai, Amanda Shin, Cécile Piot, Jiangyan Yu, Yaqi Gu, Mingnan Zhang, Caixia Gao, Lei Chen, Honglin Wang, Mathias Vétillard, Pierre Guermonprez, Immanuel Kwok, Lai Guan Ng, Svetoslav Chakarov, Andreas Schlitzer, Burkhard Becher, Charles-Antoine Dutertre, Bing Su, Florent Ginhoux

Secretomics reveals gelatinase substrates at the blood-brain barrier that are implicated in astroglial barrier function.

19/07/2023 Science advances

Authors: Miriam Burmeister, Annika Fraunenstein, Martin Kahms, Laura Arends, Hanna Gerwien, Tushar Deshpande, Tanja Kuhlmann, Catharina C Gross, Venu N Naik, Heinz Wiendl, Juergen Klingauf, Felix Meissner, Lydia Sorokin

Catecholamines and inflammation in advanced liver disease: more closely intertwined than expected?

19/07/2023 Gut

Authors: Hans Dieter Nischalke, Christina Nischalke, Franziska Schmalz, Christine Möller, Benjamin Krämer, Alexandra Funken, Adrian Goldspink, Jacob Nattermann, Christian Strassburg, Philipp Lutz

Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment.

19/07/2023 Science translational medicine

Authors: Lara Lechner, Robert Opitz, Matt J Silver, Philipp M Krabusch, Andrew M Prentice, Martha S Field, Harald Stachelscheid, Elsa Leitão, Christopher Schröder, Valeria Fernandez Vallone, Bernhard Horsthemke, Karl-Heinz Jöckel, Börge Schmidt, Markus M Nöthen, Per Hoffmann, Stefan Herms, Patrick W Kleyn, Matthias Megges, Ulrike Blume-Peytavi, Katja Weiss, Knut Mai, Oliver Blankenstein, Benedikt Obermayer, Susanna Wiegand, Peter Kühnen

Macrophage and monocyte subsets in response to ischemic stroke.

19/07/2023 European journal of immunology

Authors: Nelli Blank-Stein, Elvira Mass

TLR7/8 stress response drives histiocytosis in SLC29A3 disorders.

18/07/2023 The Journal of experimental medicine

Authors: Takuma Shibata, Ryota Sato, Masato Taoka, Shin-Ichiroh Saitoh, Mayumi Komine, Kiyoshi Yamaguchi, Susumu Goyama, Yuji Motoi, Jiro Kitaura, Kumi Izawa, Yoshio Yamauchi, Yumiko Tsukamoto, Takeshi Ichinohe, Etsuko Fujita, Ryosuke Hiranuma, Ryutaro Fukui, Yoichi Furukawa, Toshio Kitamura, Toshiyuki Takai, Arinobu Tojo, Mamitaro Ohtsuki, Umeharu Ohto, Toshiyuki Shimizu, Manabu Ozawa, Nobuaki Yoshida, Toshiaki Isobe, Eicke Latz, Kojiro Mukai, Tomohiko Taguchi, Hiroaki Hemmi, Shizuo Akira, Kensuke Miyake

Safety and efficacy of amlitelimab, a fully human, non-depleting, non-cytotoxic anti-OX40Ligand monoclonal antibody, in atopic dermatitis: results of a phase IIa randomised placebo-controlled trial.

18/07/2023 The British journal of dermatology

Authors: Stephan Weidinger, Thomas Bieber, Michael J Cork, Adam Reich, Rosamund Wilson, Sonia Quaratino, Marisa Stebegg, Nuala Brennan, Sally Gilbert, John T O'Malley, Ben Porter-Brown