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featured publications

  • Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP.

    Nature communications

    Authors: Martin F Peter, Jan A Ruland, Yeojin Kim, Philipp Hendricks, Niels Schneberger, Jan Peter Siebrasse, Gavin H Thomas, Ulrich Kubitscheck, Gregor Hagelueken

  • Hepatobiliary manifestations in patients with ulcerative colitis: a retrospective analysis.

    Frontiers in medicine

    Authors: Katharina Stratmann, Songül Aydolmus, Wenyi Gu, Dominik Heling, Ulrich Spengler, Birgit Terjung, Christian P Strassburg, Richard Vollenberg, Irina Blumenstein, Jonel Trebicka

  • The mitochondrial protease PARL is required for spermatogenesis.

    Communications biology

    Authors: Sarah Schumacher, Laura Klose, Jessica Lambertz, Dieter Lütjohann, Ronald Biemann, Stefanie Kuerten, Lars Fester

  • Adipocyte precursor-derived NRG1 promotes resistance to FGFR inhibition in urothelial carcinoma.

    Cancer research

    Authors: Sana Hosni, Viola Kilian, Niklas Klümper, Daniela Gabbia, Katharina Sieckmann, Dillon Corvino, Anja Winkler, Miriam Saponaro, Karin Woersdoerfer, Doris Schmidt, Oliver Hahn, Ilaria Zanotto, Marina Bertlich, Marieta Toma, Tobias Bald, Markus Eckstein, Michael Hölzel, Matthias Geyer, Manuel Ritter, Dagmar Wachten, Sara De Martin, Abdullah Alajati

  • Host genetic regulation of human gut microbial structural variation.

    Nature

    Authors: Daria V Zhernakova, Daoming Wang, Lei Liu, Sergio Andreu-Sánchez, Yue Zhang, Angel J Ruiz-Moreno, Haoran Peng, Niels Plomp, Ángela Del Castillo-Izquierdo, Ranko Gacesa, Esteban A Lopera-Maya, Godfrey S Temba, Vesla I Kullaya, Sander S van Leeuwen, Ramnik J Xavier, Quirijn de Mast, Leo A B Joosten, Niels P Riksen, Joost H W Rutten, Mihai G Netea, Serena Sanna, Cisca Wijmenga, Rinse K Weersma, Alexandra Zhernakova, Hermie J M Harmsen, Jingyuan Fu

  • Spectral Analysis of Human Retinal Pigment Epithelium Cells in Healthy and AMD Eyes.

    Investigative ophthalmology & visual science

    Authors: Leonie Bourauel, Marc Vaisband, Leon von der Emde, Katharina Bermond, Ioana Sandra Tarau, Rainer Heintzmann, Frank G Holz, Christine A Curcio, Jan Hasenauer, Thomas Ach

  • The pathophysiology of sepsis and precision-medicine-based immunotherapy.

    Nature immunology

    Authors: Evangelos J Giamarellos-Bourboulis, Anna C Aschenbrenner, Michael Bauer, Christoph Bock, Thierry Calandra, Irit Gat-Viks, Evdoxia Kyriazopoulou, Mihaela Lupse, Guillaume Monneret, Peter Pickkers, Joachim L Schultze, Tom van der Poll, Frank L van de Veerdonk, Alexander P J Vlaar, Sebastian Weis, W Joost Wiersinga, Mihai G Netea

  • Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation.

    The Journal of clinical investigation

    Authors: Samuel Young, Christian Schiffer, Alice Wagner, Jannika Patz, Anton Potapenko, Leonie Herrmann, Verena Nordhoff, Tim Pock, Claudia Krallmann, Birgit Stallmeyer, Albrecht Röpke, Michelina Kierzek, Cristina Biagioni, Tao Wang, Lars Haalck, Dirk Deuster, Jan N Hansen, Dagmar Wachten, Benjamin Risse, Hermann M Behre, Stefan Schlatt, Sabine Kliesch, Frank Tüttelmann, Christoph Brenker, Timo Strünker

  • Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia.

    Nature communications

    Authors: Learta Pervizaj-Oruqaj, Balachandar Selvakumar, Maximiliano Ruben Ferrero, Monika Heiner, Christina Malainou, Rolf David Glaser, Jochen Wilhelm, Marek Bartkuhn, Astrid Weiss, Ioannis Alexopoulos, Biruta Witte, Stefan Gattenlöhner, István Vadász, Rory Edward Morty, Werner Seeger, Ralph Theo Schermuly, Ana Ivonne Vazquez-Armendariz, Susanne Herold

  • Top publication

    BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination.

    Nature communications

    Authors: Krista E van Meijgaarden, Wenchao Li, Simone J C F M Moorlag, Valerie A C M Koeken, Hans J P M Koenen, Leo A B Joosten, Annapurna Vyakarnam, Asma Ahmed, Srabanti Rakshit, Vasista Adiga, Tom H M Ottenhoff, Yang Li, Mihai G Netea, Simone A Joosten