Skip to main content

T-SPOT.TB reactivity in Southern African children with and without in utero HIV exposure.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Authors: Saori C Iwase, Paul T Edlefsen, Lynnette Bhebhe, Kessy Motsumi, Sikhulile Moyo, Anna-Ursula Happel, Danica Shao, Nicholas Mmasa, Sara Schenkel, Melanie A Gasper, Melanie Dubois, Megan A Files, Chetan Seshadri, Fergal Duffy, John Aitchison, Mihai G Netea, Jennifer Jao, Donald W Cameron, Clive M Gray, Heather B Jaspan, Kathleen M Powis

Infants HIV-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared TB infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.

© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PMID: 37293702

Participating cluster members