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Trained immunity in the bone marrow: Hub of autoimmunity.

Cell stem cell

Authors: Mihai G Netea, Leo A B Joosten

An inappropriate induction of trained immunity in the bone marrow progenitors of immune cells has been described to underlie chronic inflammatory processes. Mills and colleagues' recently published paper in Cell Stem Cell shows that maladaptive trained immunity drives inflammation in autoimmune processes, opening a new area of research in autoimmunity.

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PMID: 39515297

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