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Publications

featured publications

  • Single cell whole-genome sequencing of brain cells: age- and cell-type specific mutational profiles.

    Signal transduction and targeted therapy

    Authors: Melania Capasso, N Ahmad Aziz

  • Assessing mRNA translation in mouse adult microglia and bone-marrow-derived macrophages.

    STAR protocols

    Authors: Ignazio Antignano, Lily Keane, Melania Capasso

  • Top publication

    Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.

    Cell reports

    Authors: Theodore S Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C Schaar, Lorenzo Bonaguro, Tal Pecht, Izabela Galvao, Shobhit Agrawal, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena de Domenico, Arik Horne, Chantal Donovan, Richard Y Kim, David Gallego-Ortega, Tessa E Gillett, Meshal Ansari, Jonas Schulte-Schrepping, Nina Offermann, Ignazio Antignano, Burcu Sivri, Wenying Lu, Mathew S Eapen, Martina van Uelft, Collins Osei-Sarpong, Maarten van den Berge, Hylke C Donker, Harry J M Groen, Sukhwinder S Sohal, Johanna Klein, Tina Schreiber, Andreas Feißt, Ali Önder Yildirim, Herbert B Schiller, Martijn C Nawijn, Matthias Becker, Kristian Händler, Marc Beyer, Melania Capasso, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Fabian J Theis, Philip M Hansbro, Dirk Skowasch, Joachim L Schultze

  • Aging microglia.

    Cellular and molecular life sciences : CMLS

    Authors: Ignazio Antignano, Yingxiao Liu, Nina Offermann, Melania Capasso

  • Loss of voltage-gated hydrogen channel 1 expression reveals heterogeneous metabolic adaptation to intracellular acidification by T cells.

    JCI insight

    Authors: David Coe, Thanushiyan Poobalasingam, Hongmei Fu, Fabrizia Bonacina, Guosu Wang, Valle Morales, Annalisa Moregola, Nico Mitro, Kenneth Cp Cheung, Eleanor J Ward, Suchita Nadkarni, Dunja Aksentijevic, Katiuscia Bianchi, Giuseppe Danilo Norata, Melania Capasso, Federica M Marelli-Berg

  • Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.

    Nature cell biology

    Authors: Julia P Gerber, Jenny Russ, Vijay Chandrasekar, Nina Offermann, Hang-Mao Lee, Sarah Spear, Nicola Guzzi, Simona Maida, Sundararaghavan Pattabiraman, Ruoyu Zhang, Amir H Kayvanjoo, Preeta Datta, Jagath Kasturiarachchi, Teresa Sposito, Natalia Izotova, Kristian Händler, Peter D Adams, Teresa Marafioti, Tariq Enver, Jörg Wenzel, Marc Beyer, Elvira Mass, Cristian Bellodi, Joachim L Schultze, Melania Capasso, Rachael Nimmo, Paolo Salomoni

  • Loss of mTORC2-induced metabolic reprogramming in monocytes uncouples migration and maturation from production of proinflammatory mediators.

    Journal of leukocyte biology

    Authors: Maryam Jangani, Juho Vuononvirta, Lamya Yamani, Eleanor Ward, Melania Capasso, Suchita Nadkarni, Frances Balkwill, Federica Marelli-Berg

  • Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.

    Cellular and molecular gastroenterology and hepatology

    Authors: Francesca R Delvecchio, Rachel E A Fincham, Sarah Spear, Andrew Clear, Marina Roy-Luzarraga, Frances R Balkwill, John G Gribben, Michele Bombardieri, Kairbaan Hodivala-Dilke, Melania Capasso, Hemant M Kocher

  • mTOR-dependent translation amplifies microglia priming in aging mice.

    The Journal of clinical investigation

    Authors: Lily Keane, Ignazio Antignano, Sean-Patrick Riechers, Raphael Zollinger, Anaelle A Dumas, Nina Offermann, Maria E Bernis, Jenny Russ, Frederike Graelmann, Patrick Neil McCormick, Julia Esser, Dario Tejera, Ai Nagano, Jun Wang, Claude Chelala, Yvonne Biederbick, Annett Halle, Paolo Salomoni, Michael T Heneka, Melania Capasso

  • Microglial phagocytosis in aging and Alzheimer's disease.

    Journal of neuroscience research

    Authors: Enrique Gabandé-Rodríguez, Lily Keane, Melania Capasso