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  • Top publication

    Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS.

    Nature medicine

    Authors: Madhurima Chatterjee, Selcuk Özdemir, Christian Fritz, Wiebke Möbius, Luca Kleineidam, Eckhard Mandelkow, Jacek Biernat, Cem Doğdu, Oliver Peters, Nicoleta Carmen Cosma, Xiao Wang, Luisa-Sophia Schneider, Josef Priller, Eike Spruth, Andrea A Kühn, Patricia Krause, Thomas Klockgether, Ina R Vogt, Okka Kimmich, Annika Spottke, Daniel C Hoffmann, Klaus Fliessbach, Carolin Miklitz, Cornelia McCormick, Patrick Weydt, Björn Falkenburger, Moritz Brandt, René Guenther, Elisabeth Dinter, Jens Wiltfang, Niels Hansen, Mathias Bähr, Inga Zerr, Agnes Flöel, Peter J Nestor, Emrah Düzel, Wenzel Glanz, Enise Incesoy, Katharina Bürger, Daniel Janowitz, Robert Perneczky, Boris S Rauchmann, Franziska Hopfner, Olivia Wagemann, Johannes Levin, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Johannes Prudlo, Thomas Gasser, Kathrin Brockmann, David Mengel, Milan Zimmermann, Matthis Synofzik, Carlo Wilke, Judit Selma-González, Janina Turon-Sans, Miguel Angel Santos-Santos, Daniel Alcolea, Sara Rubio-Guerra, Juan Fortea, Álvaro Carbayo, Alberto Lleó, Ricardo Rojas-García, Ignacio Illán-Gala, Michael Wagner, Ingo Frommann, Sandra Roeske, Lucas Bertram, Michael T Heneka, Frederic Brosseron, Alfredo Ramirez, Matthias Schmid, Rudi Beschorner, Annett Halle, Jochen Herms, Manuela Neumann, Nicolas R Barthélemy, Randall J Bateman, Patrizia Rizzu, Peter Heutink, Oriol Dols-Icardo, Günter Höglinger, Andreas Hermann, Anja Schneider

  • Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.

    Cells

    Authors: Jasenka Rudan Njavro, Marija Vukicevic, Emma Fiorini, Lina Dinkel, Stephan A Müller, Anna Berghofer, Chiara Bordier, Stanislav Kozlov, Annett Halle, Katrin Buschmann, Anja Capell, Camilla Giudici, Michael Willem, Regina Feederle, Stefan F Lichtenthaler, Chiara Babolin, Paolo Montanari, Andrea Pfeifer, Marie Kosco-Vilbois, Sabina Tahirovic

  • MotiQ: an open-source toolbox to quantify the cell motility and morphology of microglia.

    Molecular biology of the cell

    Authors: Jan N Hansen, Matthias Brückner, Marie J Pietrowski, Jan F Jikeli, Monika Plescher, Hannes Beckert, Mareike Schnaars, Lorenz Fülle, Katharina Reitmeier, Thomas Langmann, Irmgard Förster, Delphine Boche, Gabor C Petzold, Annett Halle

  • Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.

    The EMBO journal

    Authors: Markus P Kummer, Christina Ising, Christiane Kummer, Heela Sarlus, Angelika Griep, Ana Vieira-Saecker, Stephanie Schwartz, Annett Halle, Matthias Brückner, Kristian Händler, Joachim L Schultze, Marc Beyer, Eicke Latz, Michael T Heneka

  • Glial Purinergic Signaling in Neurodegeneration.

    Frontiers in neurology

    Authors: Marie J Pietrowski, Amr Ahmed Gabr, Stanislav Kozlov, David Blum, Annett Halle, Kevin Carvalho

  • mTOR-dependent translation amplifies microglia priming in aging mice.

    The Journal of clinical investigation

    Authors: Lily Keane, Ignazio Antignano, Sean-Patrick Riechers, Raphael Zollinger, Anaelle A Dumas, Nina Offermann, Maria E Bernis, Jenny Russ, Frederike Graelmann, Patrick Neil McCormick, Julia Esser, Dario Tejera, Ai Nagano, Jun Wang, Claude Chelala, Yvonne Biederbick, Annett Halle, Paolo Salomoni, Michael T Heneka, Melania Capasso

  • Epothilones Improve Axonal Growth and Motor Outcomes after Stroke in the Adult Mammalian CNS.

    Cell reports. Medicine

    Authors: Christof Kugler, Christian Thielscher, Bertrand A Tambe, Martin K Schwarz, Annett Halle, Frank Bradke, Gabor C Petzold

  • Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor.

    Brain : a journal of neurology

    Authors: Kevin Carvalho, Emilie Faivre, Marie J Pietrowski, Xavier Marques, Victoria Gomez-Murcia, Aude Deleau, Vincent Huin, Jan N Hansen, Stanislav Kozlov, Clément Danis, Mariana Temido-Ferreira, Joana E Coelho, Céline Mériaux, Sabiha Eddarkaoui, Stéphanie Le Gras, Mélanie Dumoulin, Lucrezia Cellai, Isabelle Landrieu, Yijuang Chern, Malika Hamdane, Luc Buée, Anne-Laurence Boutillier, Sabine Levi, Annett Halle, Luisa V Lopes, David Blum

  • Neural sphingosine 1-phosphate accumulation activates microglia and links impaired autophagy and inflammation.

    Glia

    Authors: Indulekha Karunakaran, Shah Alam, Surendar Jayagopi, Stefan J Frohberger, Jan N Hansen, Janina Kuehlwein, Benedikt V Hölbling, Beatrix Schumak, Marc P Hübner, Markus H Gräler, Annett Halle, Gerhild van Echten-Deckert

  • Inhibition of Stat3-mediated astrogliosis ameliorates pathology in an Alzheimer's disease model.

    EMBO molecular medicine

    Authors: Nicole Reichenbach, Andrea Delekate, Monika Plescher, Franziska Schmitt, Sybille Krauss, Nelli Blank, Annett Halle, Gabor C Petzold