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Publications

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  • MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma.

    Acta neuropathologica

    Authors: Lea L Friker, Thomas Perwein, Andreas Waha, Evelyn Dörner, Rebecca Klein, Mirjam Blattner-Johnson, Julian P Layer, Dominik Sturm, Gunther Nussbaumer, Robert Kwiecien, Isabel Spier, Stefan Aretz, Kornelius Kerl, Ulrike Hennewig, Marius Rohde, Axel Karow, Ingmar Bluemcke, Ann Kristin Schmitz, Harald Reinhard, Pablo Hernáiz Driever, Susanne Wendt, Annette Weiser, Ana S Guerreiro Stücklin, Nicolas U Gerber, André O von Bueren, Claudia Khurana, Norbert Jorch, Maria Wiese, Christian P Kratz, Matthias Eyrich, Michael Karremann, Ulrich Herrlinger, Michael Hölzel, David T W Jones, Marion Hoffmann, Torsten Pietsch, Gerrit H Gielen, Christof M Kramm

  • RNase T2 restricts TLR13-mediated autoinflammation in vivo.

    The Journal of experimental medicine

    Authors: Carlos Gomez-Diaz, Wilhelm Greulich, Benedikt Wefers, Meiyue Wang, Silvia Bolsega, Maike Effern, Daniel P Varga, Zhe Han, Minyi Chen, Marleen Bérouti, Natascia Leonardi, Ulrike Schillinger, Bernhard Holzmann, Arthur Liesz, Axel Roers, Michael Hölzel, Marijana Basic, Wolfgang Wurst, Veit Hornung

  • Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy.

    JAMA oncology

    Authors: Jonas Saal, Markus Eckstein, Manuel Ritter, Peter Brossart, Julian Luetkens, Jörg Ellinger, Viktor Grünwald, Michael Hölzel, Niklas Klümper

  • Tonabersat enhances temozolomide-mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition.

    Molecular oncology

    Authors: Elena N C Schmidt, Bernd O Evert, Barbara E F Pregler, Ahmad Melhem, Meng-Chun Hsieh, Markus Raspe, Hannah Strobel, Julian Roos, Torsten Pietsch, Patrick Schuss, Pamela Fischer-Posovszky, Mike-Andrew Westhoff, Michael Hölzel, Ulrich Herrlinger, Hartmut Vatter, Andreas Waha, Matthias Schneider, Anna-Laura Potthoff

  • C-Reactive Protein Facilitates Premetastatic Niche Formation in the Lungs.

    Cancer research

    Authors: Jonas Saal, Niklas Klümper, Michael Hölzel

  • The modified Glasgow Prognostic Score (mGPS) can guide decisions for immunotherapy treatment beyond progression.

    European journal of cancer (Oxford, England : 1990)

    Authors: Jonas Saal, Markus Eckstein, Manuel Ritter, Peter Brossart, Michael Hölzel, Viktor Grünwald, Niklas Klümper

  • Type I Interferon Drives a Cellular State Inert to TCR-Stimulation and Could Impede Effective T-Cell Differentiation in Cancer.

    European journal of immunology

    Authors: Dillon Corvino, Martin Batstone, Brett G M Hughes, Tim Kempchen, Susanna S Ng, Nazhifah Salim, Franziska Schneppenheim, Denise Rommel, Ananthi Kumar, Sally Pearson, Jason Madore, Lambross T Koufariotis, Lisa Maria Steinheuer, Dilan Pathirana, Kevin Thurley, Michael Hölzel, Nicholas Borcherding, Matthias Braun, Tobias Bald

  • Pre-treatment metastatic biopsy: a step towards precision oncology for urothelial cancer.

    Nature reviews. Urology

    Authors: Niklas Klümper, Alexander Cox, Gottfrid Sjödahl, Florian Roghmann, Christian Bolenz, Arndt Hartmann, Viktor Grünwald, Bishoy M Faltas, Michael Hölzel, Markus Eckstein

  • HLA-G expression associates with immune evasion muscle-invasive urothelial cancer and drives prognostic relevance.

    Frontiers in immunology

    Authors: Annalena Branz, Christian Matek, Fabienne Lange, Veronika Bahlinger, Niklas Klümper, Michael Hölzel, Pamela L Strissel, Reiner Strick, Danijel Sikic, Sven Wach, Helge Taubert, Bernd Wullich, Arndt Hartmann, Barbara Seliger, Markus Eckstein

  • Expression of the large amino acid transporter SLC7A5/LAT1 on immune cells is enhanced in primary sclerosing cholangitis-associated cholangiocarcinoma and correlates with poor prognosis in cholangiocarcinoma.

    Human pathology

    Authors: Vittorio Branchi, Racha Hosni, Lukas Kiwitz, Susanna Ng, Gemma van der Voort, Neila Bambi, Eileen Kleinfelder, Laura K Esser, Leona Dold, Bettina Langhans, Maria A Gonzalez-Carmona, Saskia Ting, Glen Kristiansen, Jörg C Kalff, Kevin Thurley, Michael Hölzel, Hanno Matthaei, Marieta I Toma