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featured publications

  • Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.

    Nature genetics

    Authors: Aeron M Small, Ta-Yu Yang, Shinsuke Itoh, Sébastien Thériault, Line Dufresne, Ryo Kurosawa, Issei Komuro, Koichi Matsuda, Ha My T Vy, Eric H Farber-Eger, Lauren Lee Shaffer, Kristin M Boulier, Kristin M Corey, Megan E Ramaker, Fabien Laporte, Jean-Jacques Schott, Solena Le Scouarnec, Sasha A Singh, Abhijeet R Sonawane, Harry A Smith, Nicholas Rafaels, Jonas Ghouse, Anna A Raja, Sisse R Ostrowski, Erik Sørensen, Christina Mikkelsen, Ole B Pedersen, Christian Erikstrup, Henrik Ullum, Gardar Sveinbjornsson, Daniel F Gudbjartsson, Erik Abner, Jiwoo Lee, Andrea Ganna, Ulrike Nowak-Göttl, Sarah Finer, Johannes Schumacher, Carlo Maj, Baravan Al-Kassou, Georg Nickenig, Teresa Trenkwalder, Martina Dreβen, Markus Krane, Markus M Nöthen, Marta R Moksnes, Ben M Brumpton, Stacey Knight, Kirk U Knowlton, Lincoln Nadauld, Radek Debiec, Muntaser D Musameh, Peter S Braund, Christopher P Nelson, Tomasz Czuba, Olle Melander, Margaret Sunitha Selvaraj, Satoshi Koyama, Rohan Bhukar, Yunfeng Ruan, Johan Ljungberg, Scott M Damrauer, Michael G Levin, Andre Franke, Klaus Berger, Christian T Ruff, Giorgio E M Melloni, Frederick K Kamanu, Kaoru Ito, Ron Do, Ruth J F Loos, Heribert Schunkert, Quinn S Wells, Svati H Shah, Thierry Le Tourneau, David Messika-Zeitoun, Christopher Gignoux, Henning Bundgaard, Susanna C Larsson, Karl Michaëlsson, Hilma Holm, Anna Helgadottir, Tonu Esko, David A van Heel, Patrick Mathieu, Nilesh J Samani, J Gustav Smith, Stefan Söderberg, Daniel J Rader, Nicholas A Marston, Marc S Sabatine, Bogdan Pasaniuc, Kelly Cho, Peter W F Wilson, Christopher J O'Donnell, Kari Stefansson, Yohan Bossé, Elena Aikawa, James C Engert, Gina M Peloso, Pradeep Natarajan, George Thanassoulis

  • Targeting the tumor cell-intrinsic ITGB2 axis inhibits melanoma progression.

    Molecular cancer

    Authors: Erik Rasbach, Laure Migayron, Anne Brandenburg, Praveen Singh, Christina Martins, Ali Kassem, Anastasia I Karkempetzaki, Nadine Suessner, Zsofi Kulcsar, Jessica Riopedre, Mariana Silva, Ethan Zhen, Shuyun Xu, Kyla Mucciarone, Julia Holzgruber, Jason B Williams, Emrullah Birgin, Mitchell P Levesque, Julia M Martínez-Gómez, Reinhard Dummer, Jennifer Landsberg, Christine G Lian, George F Murphy, Emma L Berdan, Shannan Ho Sui, Thomas S Kupper, Nuh N Rahbari, Nayoung Lee, Steven R Barthel, Tobias Schatton

  • Serum-free differentiation platform for the generation of B lymphocytes and natural killer cells from human CD34+ cord blood progenitors.

    Scientific reports

    Authors: Rigveda Bhave, Carla-Johanna Kath, Nadine Rüchel, Eleni Vasileiou, Vera H Jepsen, Katharina Raba, Aleksandra A Pandyra, Ute Fischer, Gesine Kogler

  • TALON phase IIIb study: 64 week results of brolucizumab versus aflibercept using treat-and-extend for neovascular age-related macular degeneration.

    Eye (London, England)

    Authors: Carl Regillo, Peter K Kaiser, Peter J Kertes, Mark Gillies, Tina Maio-Twofoot, David Lawrence, Frank G Holz

  • An improved porcine model of infrarenal abdominal aortic aneurysm.

    Scientific reports

    Authors: Marta Stei, Per Arkenberg, Theresa Uebing, Agnesa Mazrekaj, Joscha Mulorz, Dennis Mehrkens, Maysam Ahdab, Philipp Barnowski, Gerhard Sengle, Matti Adam, Valerie Lohner, Verena Hoerr, Ali Nahardani, Claudia Schubert-Quecke, Birgitta Mewes, Johannes Lindemeyer, Holger Grüll, Albert Busch, Sebastian Zimmer, Holger Winkels, Hubert Schelzig, Malte Kelm, Georg Nickenig, Stephan Baldus, Markus U Wagenhäuser, Martin Mollenhauer

  • Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease.

    Cardiovascular research

    Authors: Dennis Mehrkens, Johannes Dohr, Felix Sebastian Nettersheim, Felix Ballmann, Jil Bastigkeit, Alexander Brückner, Simon Geissen, Lauren De Vore, Cedric Fitsch, Chris Diekmann, Andrea de la Fuente-Alonso, Patrik Schelemei, Felix Ruben Picard, Malte Kochen, Per Arkenberg, Anna Rappenecker, Maysam Ahdab, Harshal Nemade, Suchitra Narayan, Simon Braumann, Wiebke Kreuzberg, Alexander Hof, Henning Guthoff, Benedicta Quaye Mensah, Sebastian Lechner, Andrea Guala, Artur Evangelista, Gisela Teixido-Tura, J Francisco Nistal, Miguel R Campanero, Harald Kaemmerer, Zsuzsanna Wolf, Stefan Holdenrieder, Maarten Groenink, Mitzi van Andel, Arnout Mieremet, Susanne Pfeiler, Norbert Gerdes, Ulrich Flögel, Laura-Maria Zimmermann, Gerhard Sengle, Marie-Lisa Eich, Birgid Schömig-Markiefka, Matti Adam, Bernd K Fleischmann, Daniela Wenzel, Juan Miguel Redondo, Vivian de Waard, Anna Klinke, Stephan Baldus, Martin Mollenhauer, Holger Winkels

  • Patient-Derived Monoclonal Myelin Oligodendrocyte Glycoprotein Autoantibodies Mediate Cytotoxicity.

    Neurology(R) neuroimmunology & neuroinflammation

    Authors: Nora Sandrine Wetzel, Laila Kulsvehagen, Anne-Catherine Lecourt, Beata Filipek, Patrick Lipps, Laura Rieder, Kristina Berve, Gurumoorthy Krishnamoorthy, Bert A 't Hart, Lucas Schirmer, Soumya S Yandamuri, Kevin C O'Connor, Anne-Katrin Pröbstel

  • TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis.

    Nature communications

    Authors: Massimo Vetralla, Lena Wischhof, Asrat Kahsay, Vanessa Cadenelli, Enzo Scifo, Beijia Xie, Miriana Sbrissa, Maëlle Sandhira Habert, Dan Ehninger, Rosario Rizzuto, Daniele Bano, Diego De Stefani

  • A 20-amino-acid Cardiovirus protein exhibits cytokine-mimicry activity to regulate viral replication.

    Cell reports

    Authors: Yutaro Shirasaka, Fumihiko Takeuchi, Satoshi Koike, Hiroki Kato, Takashi Fujita

  • Clinical outcomes of the PAUL® Glaucoma implant for refractory glaucoma: three-year results.

    Eye (London, England)

    Authors: Constance Liegl, Leonie Bourauel, Benjamin Aretz, Wolfgang Walz, Sarah Hundertmark, Michael Petrak, Frank G Holz, Karl Mercieca