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  • Unveiling IRF4-steered regulation of context-dependent effector programs in CD4 T cells under Th17- and Treg-skewing conditions.

    Cell reports

    Authors: Anna Gabele, Maximilian Sprang, Mert Cihan, Mareen Welzel, Assel Nurbekova, Karolina Romaniuk, Sarah Dietzen, Matthias Klein, Georg Bündgen, Maxim Emelianov, Gregory Harms, Krishnaraj Rajalingam, Tanja Ziesmann, Katrin Pape, Beatrice Wasser, David Gomez-Zepeda, Kathrin Braband, Michael Delacher, Niels Lemmermann, Stefan Bittner, Miguel A Andrade-Navarro, Stefan Tenzer, Katja Luck, Tobias Bopp, Ute Distler

  • SARS-CoV-2 surveillance in a hospital and control of an outbreak on a geriatric ward using whole genome sequencing.

    Infection prevention in practice

    Authors: Hanno Schmidt, Niels Lemmermann, Matthias Linke, Sven-Ernö Bikár, Stefan Runkel, Susann Schweiger-Seemann, Susanne Gerber, André Michel, Thomas Hankeln, Marina Veith, Wolfgang Kohnen, Bodo Plachter

  • Dual fluorescence reporter mice for Ccl3 transcription, translation, and intercellular communication.

    The Journal of experimental medicine

    Authors: Maria Belen Rodrigo, Anna De Min, Selina Kathleen Jorch, Cristina Martin-Higueras, Ann-Kathrin Baumgart, Beata Goldyn, Sara Becker, Natalio Garbi, Niels A Lemmermann, Christian Kurts

  • Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development

    Blood

    Authors: Nadine Müller-Calleja, Kristin Grunz, T Son Nguyen, Jens Posma, Denise Pedrosa, Myriam Meineck, Anne Hollerbach, Johannes Braun, Sabine Muth, Hansjörg Schild, Kathrin Saar, Norbert Hübner, Sriram Krishnaswamy, Jennifer Royce, Luc Teyton, Niels Lemmermann, Julia Weinmann-Menke, Karl J Lackner, Wolfram Ruf

  • Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation.

    Frontiers in immunology

    Authors: Rafaela Holtappels, Julia K Büttner, Kirsten Freitag, Matthias J Reddehase, Niels A Lemmermann

  • Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination.

    Frontiers in immunology

    Authors: Annkristin Heine, Niels A W Lemmermann, Chrystel Flores, Janine Becker-Gotot, Natalio Garbi, Peter Brossart, Christian Kurts

  • The effector program of human CD8 T cells supports tissue remodeling.

    The Journal of experimental medicine

    Authors: Michael Delacher, Lisa Schmidleithner, Malte Simon, Philipp Stüve, Lieke Sanderink, Agnes Hotz-Wagenblatt, Marina Wuttke, Kathrin Schambeck, Brigitte Ruhland, Veronika Hofmann, Sebastian Bittner, Uwe Ritter, Asmita Pant, Sara Salome Helbich, Morten Voss, Niels A Lemmermann, Lisa Bessiri-Schake, Toszka Bohn, Andreas Eigenberger, Ayse Nur Menevse, Claudia Gebhard, Nicholas Strieder, Hinrich Abken, Michael Rehli, Jochen Huehn, Philipp Beckhove, Thomas Hehlgans, Henrik Junger, Edward K Geissler, Lukas Prantl, Jens M Werner, Christian Schmidl, Benedikt Brors, Charles D Imbusch, Markus Feuerer

  • Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response.

    Frontiers in immunology

    Authors: Julia K Büttner, Sara Becker, Annette Fink, Melanie M Brinkmann, Rafaela Holtappels, Matthias J Reddehase, Niels A Lemmermann

  • Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells.

    PLoS pathogens

    Authors: Rafaela Holtappels, Sara Becker, Sara Hamdan, Kirsten Freitag, Jürgen Podlech, Niels A Lemmermann, Matthias J Reddehase