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Publications

featured publications

  • The Dual Mode of Antibacterial Action of the Synthetic Small Molecule DCAP Involves Lipid II Binding.

    Journal of the American Chemical Society

    Authors: Kevin C Ludwig, Jan-Samuel Puls, Cruz L Matos de Opitz, Paolo Innocenti, Jan-Martin Daniel, Jan Bornikoel, Melina Arts, Sebastian Krannich, Jan Straetener, Dominik Brajtenbach, Beate Henrichfreise, Peter Sass, Anna Mueller, Nathaniel I Martin, Heike Brötz-Oesterhelt, Ulrich Kubitscheck, Fabian Grein, Tanja Schneider

  • Biosynthesis of the corallorazines, a widespread class of antibiotic cyclic lipodipeptides.

    RSC chemical biology

    Authors: Teresa M Dreckmann, Lisa Fritz, Christian F Kaiser, Sarah M Bouhired, Daniel A Wirtz, Marvin Rausch, Anna Müller, Tanja Schneider, Gabriele M König, Max Crüsemann

  • Altering glycopeptide antibiotic biosynthesis through mutasynthesis allows incorporation of fluorinated phenylglycine residues.

    RSC chemical biology

    Authors: Irina Voitsekhovskaia, Y T Candace Ho, Christoph Klatt, Anna Müller, Daniel L Machell, Yi Jiun Tan, Maxine Triesman, Mara Bingel, Ralf B Schittenhelm, Julien Tailhades, Andreas Kulik, Martin E Maier, Gottfried Otting, Wolfgang Wohlleben, Tanja Schneider, Max Cryle, Evi Stegmann

  • Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity.

    Science translational medicine

    Authors: Emma van Groesen, Elma Mons, Ioli Kotsogianni, Melina Arts, Kamaleddin H M E Tehrani, Nicola Wade, Vladyslav Lysenko, Floor M Stel, Jordy T Zwerus, Stefania De Benedetti, Alexander Bakker, Parichita Chakraborty, Mario van der Stelt, Dirk-Jan Scheffers, Jairo Gooskens, Wiep Klaas Smits, Kirsty Holden, Peter S Gilmour, Joost Willemse, Christopher A Hitchcock, J G Coen van Hasselt, Tanja Schneider, Nathaniel I Martin

  • Sophisticated natural products as antibiotics.

    Nature

    Authors: Kim Lewis, Richard E Lee, Heike Brötz-Oesterhelt, Sebastian Hiller, Marina V Rodnina, Tanja Schneider, Markus Weingarth, Ingo Wohlgemuth

  • A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Ned P Buijs, Halana C Vlaming, Ioli Kotsogianni, Melina Arts, Joost Willemse, Yunhao Duan, Francesca M Alexander, Stephen A Cochrane, Tanja Schneider, Nathaniel I Martin

  • Synthesis of Bisindole Alkaloids and Their Mode of Action against Methicillin-Resistant .

    ACS infectious diseases

    Authors: Emmanuel T Adeniyi, Marco Kruppa, Stefania De Benedetti, Kevin C Ludwig, Violetta Krisilia, Tobias R Wassenberg, Melissa Both, Tanja Schneider, Thomas J J Müller, Rainer Kalscheuer

  • The MraY Inhibitor Muraymycin D2 and Its Derivatives Induce Enlarged Cells in Obligate Intracellular and and Break the Persistence Phenotype in .

    Antibiotics (Basel, Switzerland)

    Authors: Iris Löckener, Lara Vanessa Behrmann, Jula Reuter, Andrea Schiefer, Anna Klöckner, Sebastian Krannich, Christian Otten, Katja Mölleken, Satoshi Ichikawa, Achim Hoerauf, Tanja Schneider, Kenneth M Pfarr, Beate Henrichfreise

  • Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action.

    The ISME journal

    Authors: Jan-Samuel Puls, Benjamin Winnerling, Jeffrey John Power, Annika Marie Krüger, Dominik Brajtenbach, Matthew Johnson, Kevser Bilici, Laura Camus, Thomas Fließwasser, Tanja Schneider, Hans-Georg Sahl, Debnath Ghosal, Ulrich Kubitscheck, Simon Heilbronner, Fabian Grein

  • An antibiotic from an uncultured bacterium binds to an immutable target.

    Cell

    Authors: Rhythm Shukla, Aaron J Peoples, Kevin C Ludwig, Sourav Maity, Maik G N Derks, Stefania De Benedetti, Annika M Krueger, Bram J A Vermeulen, Theresa Harbig, Francesca Lavore, Raj Kumar, Rodrigo V Honorato, Fabian Grein, Kay Nieselt, Yangping Liu, Alexandre M J J Bonvin, Marc Baldus, Ulrich Kubitscheck, Eefjan Breukink, Catherine Achorn, Anthony Nitti, Christopher J Schwalen, Amy L Spoering, Losee Lucy Ling, Dallas Hughes, Moreno Lelli, Wouter H Roos, Kim Lewis, Tanja Schneider, Markus Weingarth